自体乳糜脂肪移植在面部年轻化中的临床应用OA

Objective To explore the clinical efficacy of autologous chylous fat transplantation in improving facial wrinkles,skin laxity,and enlarged pores in subjects with moderate to severe facial photoaging,as well as to ascertain its clinical applicability and safety.Methods A total of 20 subjects with moderate to severe facial photoaging admitted to our hospital from June 2023 to July 2024 were enrolled,all of whom underwent autologous chylous fat transplantation.Fat was harvested from their thighs or abdomen,purified,and emulsified into chylous fat,which was then precisely injected into the areas with facial wrinkles and enlarged pores.Before surgery and three months after surgery,Glogau's four-grade photoaging classification was used to evaluate the grade of facial wrinkles.An ElastiMeter skin firmness tester was employed to measure skin firmness,while a five-point photographic scale was used to quantitatively assess pore improvement.The oc-currence of postoperative complications was recorded.Results At 3 months after surgery,the av-erage grade of facial wrinkles decreased from 3.52±0.80 preoperatively to 2.03±0.30(t=0.43,P=0.011).Skin firmness increased from 20.34±3.80 to 29.51±5.50(t=0.32,P=0.001),and the average grade of pores reduced from 3.70±1.21 to 2.10±1.01(t=0.65,P=0.012).Postoperatively,there were 1 case of edema and 1 case of fat necrosis,with no serious adverse events observed.Conclusions Autologous chylous fat transplantation can significantly im-prove wrinkles,skin laxity,and enlarged pores caused by facial photoaging.The incidence of postoperative complications was low,indicating that this treatment is safe and effective for the treatment of facial photoaging.