首页|期刊导航|检验医学与临床|强脉冲光+茶树精油湿巾+睑板腺按摩治疗蠕形螨性睑缘炎的疗效观察

强脉冲光+茶树精油湿巾+睑板腺按摩治疗蠕形螨性睑缘炎的疗效观察OA

Observation on the efficacy of intense pulsed light+tea tree oil wipes+meibomian gland massage in the treatment of demodex blepharitis

中文摘要英文摘要

目的 分析强脉冲光(IPL)+茶树精油(TTO)湿巾+睑板腺按摩(MGE)治疗蠕形螨性睑缘炎的临床疗效.方法 选取2023年2月至2024年12月在该院门诊确诊为蠕形螨性睑缘炎的患者55例(106眼)作为研究对象,依据患者接受的治疗方案,将其分为对照组[MGE+TTO湿巾治疗,26例(51眼)]和联合治疗组[IPL+MGE+TTO湿巾治疗,29例(55眼)].于治疗前及治疗8周后,检测患者的蠕形螨数量、泪膜破裂时间(TBUT),并评估眼表疾病指数(OSDI)评分、睑板腺开口堵塞评分、睑板腺分泌物性状评分.结果 治疗后2组OSDI、睑板腺开口堵塞及睑板腺分泌物性状评分低于治疗前,且联合治疗组低于对照组,差异均有统计学意义(P<0.05).治疗前2组TBUT比较,差异有统计学意义(P<0.05).治疗后2组TBUT长于治疗前,且联合治疗组TBUT长于对照组,差异均有统计学意义(P<0.05).治疗后联合治疗组ΔTBUT高于对照组(P<0.05).治疗后2组蠕形螨数量少于治疗前,且联合治疗组少于对照组,差异均有统计学意义(P<0.05).结论 IPL+TTO湿巾+MGE是治疗蠕形螨性睑缘炎的一种高效的综合方案.与传统的MGE联合TTO湿巾相比,该联合模式能改善患者的临床症状与眼表体征,具有重要的临床推广价值.

Objective To analyze the clinical efficacy of intense pulsed light(IPL)+tea tree oil(TTO)wipes+meibomian gland massage(MGE)in the treatment of demodex blepharitis.Methods A total of 55 patients(106 eyes)diagnosed with demodex blepharitis in the outpatient department of the hospital from Feb-ruary 2023 to December 2024 were selected as the research subjects.According to the treatment plan received by the patients,they were divided into the control group[MGE+TTO wipes treatment,26 cases(51 eyes)]and the combined treatment group[IPL+MGE+TTO wipes treatment,29 cases(55 eyes)].Before treatment and 8 weeks after treatment,the number of demodex mites,tear film break-up time(TBUT)of the patients were detected,and the Ocular Surface Disease Index(OSDI)score,Meibomian Gland Opening Obstruction score and Meibomian Gland Secretion Quality score of the patients were evaluated.Results After treatment,the OSDI,Meibomian Gland Opening Obstruction score and Meibomian Gland Secretion Quality score of both groups were lower than those before treatment,and those in the combined treatment group were lower than those in the control group,with statistically significant differences(P<0.05).There was a statistically signif-icant difference in TBUT between the two groups before treatment(P<0.05).After treatment,the TBUT of both groups was longer than that before treatment,and the TBUT of the combined treatment group was lon-ger than that of the control group,with statistically significant differences(P<0.05).After treatment,the ΔTBUT of the combined treatment group was higher than that of the control group(P<0.05).After treat-ment,the number of demodex mites in both groups was less than that before treatment,and that in the com-bined treatment group was less than that the the control group,with statistically significant differences(P<0.05).Conclusion IPL+TTO wipes+MGE is an efficient comprehensive treatment plan for demodex bleph-aritis.Compared with MGE combined with TTO wipes,this combined mode can improve the clinical symp-toms and ocular surface signs of patients and has important clinical promotion value.

严红;高利霞;杨思思;杨于力

陆军军医大学第一附属医院眼科,重庆 400038陆军军医大学第一附属医院眼科,重庆 400038陆军军医大学第一附属医院眼科,重庆 400038陆军军医大学第一附属医院眼科,重庆 400038

医药卫生

蠕形螨性睑缘炎强脉冲光茶树精油睑板腺功能障碍物理治疗

demodex blepharitisintense pulsed lighttea tree oilmeibomian gland dysfunctionphysical therapy

《检验医学与临床》 2026 (9)

1172-1176,5

国家自然科学基金面上项目(82271055)重庆市科卫联合医学科研面上项目(2022MSXM051).

10.3969/j.issn.1672-9455.2026.09.004

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