首页|期刊导航|实用临床医药杂志|改良全视网膜激光光凝术治疗白内障合并重度非增殖期糖尿病视网膜病变患者的临床效果

改良全视网膜激光光凝术治疗白内障合并重度非增殖期糖尿病视网膜病变患者的临床效果OA

Clinical efficacy of modified panretinal photocoagulation in treating patients with cataract complicated by severe non-proliferative diabetic retinopathy

中文摘要英文摘要

目的 探讨改良全视网膜激光光凝术治疗白内障合并重度非增殖期糖尿病视网膜病变(sNPDR)的有效性与安全性.方法 选取白内障合并sNPDR患者130例作为研究对象.采用随机数字表法将患者分为改良组65例和对照组65例.改良组采用改良全视网膜激光光凝术,对照组采用传统全视网膜激光光凝术.收集2组患者的一般资料.比较2组患者的黄斑中心凹视网膜厚度(CFT)、最佳矫正视力(BCVA)、视网膜无灌注区面积(ARN)、眼压(IOP)以及并发症发生情况.结果 术后1、3、6个月,2组BCVA(LogMAR)低于术前;改良组CFT、BCVA(LogMAR)低于对照组,差异有统计学意义(P<0.05).术后1、3、6个月,2组ARN小于术前,且改良组小于对照组,差异有统计学意义(P<0.05).术后1、3、6个月,改良组的IOP波动幅度小于对照组,差异有统计学意义(P<0.05).改良组并发症总发生率为15.38%,低于对照组的30.77%,差异有统计学意义(x2=4.333,P=0.037).结论 改良全视网膜激光光凝术治疗sNPDR合并白内障优于传统术式,可更有效地改善CFT、BCVA和ARN,减小IOP波动,且安全性相当,是该类患者个体化治疗的优选方案.

Objective To investigate the efficacy and safety of modified panretinal photocoagula-tion in treating patients with cataract complicated by severe non-proliferative diabetic retinopathy(sNPDR).Methods A total of 130 patients with cataract complicated by sNPDR were selected as the study subjects.Using a random number table method,the patients were divided into modified group(n=65)and control group(n=65).The modified group underwent modified panretinal photo-coagulation,while the control group received conventional panretinal photocoagulation.General data of patients in both groups were collected.Comparisons were made between the two groups regarding central foveal thickness(CFT),best-corrected visual acuity(BCVA),area of retinal non-perfusion(ARN),intraocular pressure(IOP)and the occurrence of complications.Results At 1-,3-and 6-month postoperatively,the BCVA(LogMAR)of both groups was lower than that before the operation;the CFT and BCVA(LogMAR)of the modified group were lower than those of the control group,and the difference was statistically significant(P<0.05).At 1-,3-and 6-month postoperatively,the ARN in both groups was significantly smaller than that preoperatively,and the value in the modified group was significantly smaller than that in the control group(P<0.05).At 1-,3-and 6-month postoper-atively,the fluctuation range of IOP in the modified group was significantly smaller than that in the control group(P<0.05).The overall complication rate in the modified group was 15.38%,which was significantly lower than 30.77%in the control group(x2=4.333,P=0.037).Conclusion Modified panretinal photocoagulation is superior to conventional panretinal photocoagulation in treating sNPDR complicated by cataract.It can more effectively improve CFT,BCVA,and ARN,reduce IOP fluc-tuations,and offers comparable safety.Thus,it is the preferred option for individualized treatment of such patients.

朱芙蓉;喻娟;周丽琼;杨冬珍;程惠;陈向东;谭甘露

湖南中医药大学第一附属医院眼科,湖南长沙,410007湖南中医药大学第一附属医院眼科,湖南长沙,410007湖南中医药大学第一附属医院眼科,湖南长沙,410007湖南中医药大学第一附属医院眼科,湖南长沙,410007湖南中医药大学第一附属医院眼科,湖南长沙,410007湖南中医药大学第一附属医院眼科,湖南长沙,410007湖南中医药大学第一附属医院眼科,湖南长沙,410007

医药卫生

改良全视网膜激光光凝术重度非增殖期糖尿病视网膜病变白内障眼压视网膜无灌注区面积黄斑中心凹视网膜厚度最佳矫正视力并发症

modified panretinal photocoagulationsevere non-proliferative diabetic retinopathycataractintraocular pressurearea of retinal non-perfusioncentral foveal thicknessbest-corrected visual acuitycomplications

《实用临床医药杂志》 2026 (7)

48-53,6

国家自然科学基金面上项目(82374525)

10.7619/jcmp.20256930

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