床旁超声预测ICU脓毒症休克患者容量反应性的临床价值OA
Clinical value of bedside ultrasound in predicting volume responsiveness in patients with septic shock in ICU
目的 探讨床旁超声对ICU脓毒症休克(SS)患者容量反应性的预测价值.方法 回顾性分析 2023 年 8 月至2025 年 8 月北京市昌平区中医医院 ICU 收治的 68 例 SS 患者临床资料,根据容量反应阳性将患者分为试验组(n=36)和对照组(n=32).所有患者均接受床旁超声检查,比较两组患者容量负荷试验前超声指标差异及其与心脏指数的增加量(ΔCI)之间的相关性,并绘制受试者工作特征(ROC)曲线,分析各超声指标对 SS 患者容量反应性预测效能.结果 试验组容量负荷试验前颈动脉峰流速变异度(ΔCDPV)、颈动脉血流量变异度(ΔCBF)、下腔静脉内径变异度(ΔIVCd)均高于对照组,差异有统计学意义(P<0.05).SS患者 ΔCDPV、ΔIVCd、ΔCBF与 ΔCI均呈正相关(P<0.05).ΔCDPV、ΔIVCd、ΔCBF 预测 SS 患者容量反应性的曲线下面积(AUC)分别为 0.721、0.687、0.845,其中 ΔCBF 预测 SS 患者容量反应性的灵敏度为 0.722,特异度为 0.937,约登指数为 0.659,均高于其他指标.结论 床旁超声 ΔCDPV、ΔIVCd、ΔCBF指标均是预测 SS患者容量反应性的有效指标,其中 ΔCBF预测价值最高.
Objective To explore the predictive value of bedside ultrasound for the volume responsiveness of patients with septic shock(SS)in the ICU.Methods The clinical data of 68 patients with SS admitted to the ICU of Changping District Traditional Chinese Medicine Hospital from August 2023 to August 2025 were retrospectively analyzed.The patients were divided into the experimental group(n=36)and the control group(n=32)based on positive volume responsiveness.All patients underwent bedside ultrasound examination.The differences in ultrasound indicators before the volume load test between the two groups and their correlation with increased cardiac index(ΔCI)were compared.The receiver operating characteristic(ROC)curve was drawn to analyze the predictive efficacy of each ultrasound indicator for the volume responsiveness of SS patients.Results The carotid Doppler peak velocity variation(ΔCDPV),the carotid blood flow variation(ΔCBF),and the delta inferior vena cava diameter(ΔIVCd)before the volume load test in the experimental group were higher than those in the control group,and the differences were statistically significant(P<0.05).ΔCDPV,ΔIVCd,and ΔCBF of SS patients were positively correlated with ΔCI(P<0.05).The area under curve(AUC)of ΔCDPV,ΔIVCd,and ΔCBF for predicting the volume responsiveness of SS patients were 0.721,0.687,and 0.845,respectively.Among them,ΔCBF had the highest predictive sensitivity(0.722),specificity(0.937),and Youden index(0.659),all of which were higher than other indicators.Conclusion The ultrasound indicators ΔCDPV,ΔIVCd,and ΔCBF of bedside ultrasound are all effective indicators for predicting the volume responsiveness of SS patients.Among them,ΔCBF has the highest predictive value.
刘欣;孙亚玲;谷未强;张振宝;张淑莲;赵荣博
北京市昌平区中医医院重症医学科,北京 102200北京市昌平区中医医院重症医学科,北京 102200北京市昌平区中医医院重症医学科,北京 102200北京市昌平区中医医院重症医学科,北京 102200北京市昌平区中医医院重症医学科,北京 102200北京市昌平区中医医院重症医学科,北京 102200
医药卫生
脓毒症休克容量反应性床旁超声颈动脉血流量变异度
Septic shockVolume responsivenessBedside ultrasoundCarotid blood flow variation
《中国当代医药》 2026 (10)
20-24,5
北京市总工会职工创新项目(2021165)北京市昌平区中医医院科研课题(CZ202210).
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