上海市宝山区甲状腺癌相关危险因素病例对照研究OA

Objective To explore the risk factors of thyroid cancer in Baoshan District,Shanghai,and provide the scientific basis for treatment and prevention of thyroid cancer.Methods The thyroid cancer patients diagnosed in the Shanghai Cancer Registration System from 2019 to 2020 with registered residence and residence in Baoshan District were included in the case group,and the residents of the same sex,living in the same neighborhood committee as the selected patients and not suffering from thyroid cancer aged more than 3 years were included in the control group.A total of 190 pairs were selected for case-control study.Results The results of the multi factor logistic regression analysis of the total population showed that obesity,hair dyeing,frequent staying up late,sleeping with the light on,sulking,disharmony in marital life,history of X-ray examination,thyroid cancer in immediate family members,and other malignant tumors in immediate family members all increased the risk of thyroid cancer.The results of the multivariate logistic regression analysis of female research subjects with added physiological factors showed that compared with the general population,in addition to frequent staying up late,disharmony in marital life,and direct relatives not being included as independent risk factors for thyroid cancer,three factors of unwillingness to confide in others when having concerns,induced abortion,and taking contraceptive pills also increased the risk of thyroid cancer.Other risk factors were consistent with the general population.Conclusion The risk of thyroid cancer in Baoshan District appears to be associated with multiple factors including obesity,hair dyeing,sleeping with the light on,emotional suppression,marital issues,radiation exposure history,family history of cancer,and specific female health interventions.These findings highlight the need for targeted public health attention and interventions in this area.