马尾连对变异链球菌的体外抑菌活性研究OA
Study on Antibacterial Activity of Thalictrum foliolosum against Streptococcus mutans in Vitro
文章集中研究马尾连对变异链球菌(Streptococcus mutans,S.mutans)的体外抑菌活性.结果显示,马尾连对S.mutans的抑菌圈大小为14.78±0.46 mm,最小抑菌浓度(MIC)和最低杀菌浓度(MBC)分别为7.81 mg/mL和31.25 mg/mL,对S.mutans 表现出显著的抑菌活性.当马尾连质量浓度≥1.95 mg/mL时,其对S.mutans 的黏附作用抑制显著;当马尾连质量浓度≥0.98 mg/mL 时,其对 S.mutans 的产酸作用有不同程度的影响;当马尾连质量浓度≥1.95 mg/mL时,能显著抑制 S.mutans 生物膜形成量.马尾连对 S.mutans 具有显著的抑制及杀灭作用,并对 S.mutans 的黏附、产酸和生物膜形成量有不同程度的抑制作用.
This paper investigated the antibacterial activity of Thalictrum foliolosum against Streptococcus mutans(S.mutans)in vitro.The results indicated that diameter of the inhibition zone of Thalictrum foliolosum against S.mutans was 14.78±0.46 mm.The MIC and MBC were found to be 7.81 mg/mL and 31.25 mg/mL,respectively.The Thalictrum foliolosum demonstrated significant antibacterial activity against S.mutans.When the concentration of Thalictrum foliolosum was≥1.95 mg/mL,it demonstrated significant inhibition of S.mutans.When the concentration of Thalictrum foliolosum was≥0.98 mg/mL,it had varying degrees of influence on the acid production effect of S.mutans.When the concentration of Thalictrum foliolosum was≥1.95 mg/mL,it significantly inhibited the biofilm formation of S.mutans.Thalictrum foliolosum exerts significant inhibitory and bactericidal effects on S.mutans,and has varying degrees of inhibition on the adhesion,acid production and biofilm formation of S.mutans.
黄瑶瑶;刘玉英;丁叶;黄燕;李琳;农清栋
广西中医药大学,南宁 530200深圳七鲜信息技术有限公司罗湖太白路店,深圳 518019广西中医药大学,南宁 530200广西中医药大学,南宁 530200广西中医药大学,南宁 530200广西中医药大学,南宁 530200||广西高发传染病中西医结合转化医学重点实验室,南宁 530200||广西中医药大学第二附属医院,南宁 530011
马尾连变异链球菌生物膜体外抑菌活性
Thalictrum foliolosumStreptococcus mutansbiofilmantibacterial activity in vitro
《工业微生物》 2026 (2)
4-7,4
广西中管局科研课题(编号:GXZYA20220126)广西中医药大学大学生创新训练计划项目资助(S202310600063202410600007).
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