基于随机对照试验真武汤治疗老年慢性心力衰竭临床疗效的Meta分析OA

Objective A meta-analysis-based investigation into the clinical efficacy and safety of Zhenwu Decoction in trea-ting chronic heart failure in the elderly.Methods The system searches Chinese and English databases such as CNKI,China Biomed-ical Literature Service System,Wanfang,Chinese Medical Journals Network,China Clinical Trial Registry,International Traditional Medicine Clinical Trial Registration Platform,CSTJ,the Cochrane Library,Embase,PubMed,and Web of Science,with data collec-tion up to November 2025,to include randomized controlled trials on the treatment of chronic heart failure in the elderly with Zhenwu Decoction.Meta-analysis of the data was conducted using RevMan 5.4 and Stata 18.0 software.Results 17 randomized controlled clinical studies were included with a total sample size of 1 782 patients,with 891 patients in the experimental group and 891 patients in the control group.The meta-analysis results showed statistically significant differences between the two groups of patients in terms of clinical efficacy,TCM syndrome scores,left ventricular ejection fraction,left ventricular end-diastolic diameter,left ventricular end-systolic diameter,N-terminal pro-B-type natriuretic peptide,and incidence of adverse reactions(P<0.05).Conclusion Zhenwu Decoction has definite clinical efficacy and good safety in treating elderly chronic heart failure,reducing the incidence of adverse reac-tions.