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骨质疏松症合并常见老年慢性病管理专家共识OA

Expert consensus on the management of osteoporosis combined with common chronic diseases in older adults

中文摘要英文摘要

我国目前已步入超老龄化社会,骨质疏松症(OP)作为老年人高发疾病,约95%的患者合并至少一种其他老年慢性病.合并病会加剧OP病情、升高骨质疏松性骨折风险,给临床诊疗管理带来诸多挑战.鉴于当前缺乏统一规范,多学科专家依据循证证据制定本推荐意见,聚焦OP与心脑血管疾病、消化系统疾病、炎症性关节病、呼吸系统疾病、肿瘤五大类慢性病的共病管理.内容涵盖发病关联、危险因素、药物相互作用及综合干预,核心推荐包括:针对高风险人群强化OP筛查,治疗时兼顾"骨-慢性病"双向影响以精准选药,实施生活方式干预、营养补充与基础疾病管控相结合的综合方案.本推荐旨在为医务人员提供实践指导,促进多学科协同管理.

China has entered a super-aging society,and osteoporosis(OP),a highly prevalent condition among older adults,is frequently accompanied by other chronic diseases.Approximately 95%of patients with osteoporosis have at least one additional chronic condition.These comorbidities may exacerbate the progression of osteoporosis,increase the risk of osteoporotic fractures,and pose significant challenges for clinical management.Given the lack of standardized guidelines for the integrated management of osteoporosis with common chronic diseases,a multidisciplinary panel of experts developed the present consensus recommendations based on available evidence.This consensus focuses on the comorbidity management of osteoporosis with five major categories of chronic diseases,including cardiovascular and cerebrovascular diseases,digestive system diseases,inflammatory arthropathies,respiratory diseases,and malignancies.The recommen-dations address disease associations,shared risk factors,potential drug interactions,and comprehensive management strat-egies.Key recommendations include strengthening osteoporosis screening among high-risk populations,optimizing thera-peutic strategies by considering the bidirectional interactions between osteoporosis and comorbid chronic diseases,and im-plementing integrated management approaches that combine lifestyle modification,nutritional supplementation,and opti-mal control of underlying diseases.This consensus aims to provide practical guidance for healthcare professionals and to promote multidisciplinary collaborative management of osteoporosis in older adults with chronic comorbidities.

广东省医师协会老年医学科医师分会;广东省医学会骨质疏松学分会

医药卫生

骨质疏松症老年慢性病合并病推荐意见

osteoporosischronic diseases in older adultscomorbidityexpert consensus

《广东医学》 2026 (4)

481-489,9

国家自然科学基金面上项目(82575099)广州市重点研发计划项目(2025B03J0054)

10.13820/j.cnki.gdyx.20254366

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