首页|期刊导航|阿尔茨海默病及相关病|老年痴呆合并脑卒中后偏瘫患者深静脉血栓发生的危险因素分析

老年痴呆合并脑卒中后偏瘫患者深静脉血栓发生的危险因素分析OA

Analysis of risk factors for deep venous thrombosis in elderly patients with dementia complicated by post-stroke hemiplegia

中文摘要英文摘要

目的:探讨老年痴呆合并脑卒中后偏瘫患者深静脉血栓发生的危险因素.方法:回顾性分析 2024 年 1 月~2025年8月医院收治的100例老年痴呆合并脑卒中后偏瘫患者.按照是否发生深静脉血栓(DVT)将其分成DVT组(n=40)与非DVT组(n=60).比较两组的卒中相关指标、治疗与护理因素、实验室指标,多因素分析DVT的危险、保护因素.结果:两组患者的神经功能缺损(NIHSS)评分、偏瘫肢体肌力分级、卧床时间、开始康复治疗时间、是否使用脱水剂、是否预防性使用抗凝药物、D-二聚体、纤维蛋白原(FIB)、血小板计数(PLT)、凝血酶原时间(PT)、活化部分凝血活酶时间(APTT)比较,差异均有统计学意义(P<0.05).结论:老年痴呆合并脑卒中后偏瘫患者DVT 的发生与多种因素密切相关.卒中严重程度高、重度瘫痪、长时间卧床、使用脱水剂及高 D-二聚体、高 FIB、PT/APTT 缩短是 DVT 的独立危险因素,而早期康复治疗和预防性使用抗凝药物是重要的独立保护因素.

Objective:To explore the retrospective risk factors for deep venous thrombosis(DVT)in elderly patients with dementia complicated by post-stroke hemiplegia.Compare the stroke-related indicators,treatment and nursing factors,and laboratory parameters between the two groups,and perform multivariate analysis to identify the risk and protective factors for DVT.Compare the stroke-related indicators,treatment and nursing factors,and laboratory parameters between the two groups,and perform multivariate analysis to identify the risk and protective factors for DVT.Methods:A retrospective analysis was conducted on 100 elderly patients with dementia and post-stroke hemiplegia who visited our hospital from January 2024 to August 2025.They were divided into a thrombosis group(n=40)and a non-thrombosis group(n=60)based on whether they developed DVT.The general characteristics,stroke-related indicators,treatment and nursing factors,and laboratory indicators between the two groups were compared.Multivariate analysis was performed to identify risk and protective factors for DVT.Results:zStroke severity,severe paralysis,prolonged bed rest,diuretic use,elevated D-dimer,high FIB,and shortened PT/APTT were independent risk factors for DVT.Early rehabilitation and prophylactic anticoagulation were significant independent protective factors(P<0.05).Conclusions:The occurrence of DVT in elderly patients with dementia complicated by post-stroke hemiplegia is closely associated with multiple factors.Severe stroke,profound paralysis,prolonged bed rest,diuretic use,elevated D-dimer,high fibrinogen,and shortened PT/APTT are independent risk factors for DVT,while early rehabilitation and prophylactic anticoagulation represent significant independent protective factors.

华玲洁

杭州市第三人民医院,浙江 杭州 310000

医药卫生

老年痴呆脑卒中偏瘫深静脉血栓

DementiaStrokeHemiplegiaDeep vein thrombosis

《阿尔茨海默病及相关病》 2026 (3)

173-176,185,5

10.3969/j.issn.2096-5516.2026.03.005

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