2026年美国儿科学会《新生儿缺氧缺血性脑病亚低温治疗的临床报告》解读OA
Interpretation of 2026"Therapeutic Hypothermia for Neonatal Hypoxic-Ischemic Encephalopa-thy:Clinical Report"published by American Academy of Pediatrics
新生儿缺氧缺血性脑病(hypoxic-ischemic encephalopathy,HIE)是围生期窒息导致的严重的神经系统损伤性疾病.亚低温治疗可显著降低中重度HIE患儿的死亡率及远期严重神经系统不良结局发生风险.2026年2月,美国儿科学会发布《新生儿缺氧缺血性脑病亚低温治疗的临床报告》(以下简称《美国2026报告》),在《低体温和新生儿脑病》(以下简称《美国2014报告》)基础上,结合高质量循证证据,对亚低温治疗实施策略及综合管理进行了系统更新.本文结合《美国2014报告》及我国《亚低温治疗新生儿缺氧缺血性脑病专家共识(2022)》,对《美国2026报告》进行对比解读,以供临床实践参考.
Neonatal hypoxic-ischemic encephalopathy(HIE)is a severe neurological injury caused by perinatal asphyxia events.Therapeutic hypothermia has been proven to significantly reduce the mortality and the risk of long-term severe neurodevelopmental impairment in infants with moderate-to-severe HIE.In February 2026,the American Academy of Pediatrics published Therapeutic Hypothermia for Neonatal Hypoxic-Ischemic Encephalopathy:Clinical Report(American 2026 report).Incorporating high-quality evidence from recent clinical researches,American 2026 report provides systematic updates on the implementation strategies and comprehensive management of therapeutic hypothermia based on Hypothermia and Neonatal Encephalopathy(American 2014 report).This article offers a comparative interpretation of American 2026 report in conjunction with American 2014 report and Expert Consensus on Therapeutic Hypothermia in Neonates with Hypoxic Ischemic Encephalopathy(2022)in China,with the aim of benefiting clinical practice.
陈乡;张国庆;胡黎园;程国强;周文浩;蒋思远;贝斐
上海交通大学医学院附属上海儿童医学中心新生儿科 上海,200127上海交通大学医学院附属上海儿童医学中心新生儿科 上海,200127复旦大学附属儿科医院新生儿科 上海,201102复旦大学附属儿科医院新生儿科 上海,201102广州医科大学附属妇女儿童医疗中心新生儿科 广州,510623复旦大学附属儿科医院新生儿科 上海,201102上海交通大学医学院附属上海儿童医学中心新生儿科 上海,200127
新生儿缺氧缺血性脑病亚低温治疗新生儿
Hypoxic-ischemic encephalopathyTherapeutic hypothermiaNeonates
《中国循证儿科杂志》 2026 (2)
94-99,6
2024年国家重点研发计划:2024YFC2707700,2024YFC2707701
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