首页|期刊导航|中国食物与营养|维生素D加钙制剂联合膳食指导对营养性维生素D缺乏性佝偻病患儿的临床疗效

维生素D加钙制剂联合膳食指导对营养性维生素D缺乏性佝偻病患儿的临床疗效OA

Clinical Efficacy of Vitamin D Plus Calcium Preparation Combined with Dietary Guidance in Children with Nutritional Vitamin D Deficiency Rickets

中文摘要英文摘要

目的:探究维生素 D加钙制剂联合膳食指导对营养性维生素 D缺乏性佝偻病患儿的临床疗效.方法:选取2020年4月—2023年4月期间西安市第三医院儿科门诊收治的80例营养性维生素D缺乏性佝偻病患儿为研究对象,通过随机数表法分组研究,每组40例.对照组仅予以维生素D加钙制剂治疗,观察组予以维生素D加钙制剂及膳食指导联合治疗.对比两组患儿的临床疗效、骨代谢指标、骨密度.结果:观察组患儿治疗3个月后的临床总有效率(95.00%)明显比对照组(77.50%)高(P<0.05);观察组患儿治疗3个月后的BALP水平明显比对照组高,其BGP、NBAP水平明显低于对照组(P<0.05);观察组患儿治疗3个月后的桡骨、尺骨的骨密度值明显比对照组高(P<0.05).结论:对营养性维生素D缺乏性佝偻病患儿采取维生素D、钙制剂及膳食指导联合治疗方案值得推荐.

[Objective]To explore the clinical effect of vitamin D plus calcium preparation combined with dietary guidance on children with nutritional vitamin D deficiency rickets.[Method]A total of 80 children with nutritional vitamin D deficiency rickets admitted to the pediatric outpatient department of Xi'an Third Hospital from April 2020 to April 2023 were selected as the study objects,with 40 cases in each group grouped by random number table method.The control group was treated with vitamin D plus calcium preparation,and the observation group was treated with vitamin D plus calcium preparation and dietary guidance.The clinical ef-ficacy,bone metabolism index and bone density were compared between the two groups.[Result]The total clini-cal effective rate(95.00%)of the observation group children after 3 months of treatment was significantly higher than that of the control group(77.50%)(P<0.05).The BALP levels of the observation group children after 3 months of treatment were significantly higher than those of the control group,with BGP and NBAP levels significantly lower than those of the control group(P<0.05).The bone density values of the radius and ulna in the observation group children after 3 months of treatment were significantly higher than those of the control group(P<0.05).[Conclusion]The combination treatment of vitamin D,calcium preparation and dietary guidance for children with nutritional vitamin D deficiency rickets is highly effective and safe,and worthy of recommendation.

闫敏;刘燕燕

西安市第三医院儿科,西安 710081西安市第三医院儿童保健科,西安 710081

佝偻病维生素D钙制剂膳食指导骨密度

ricketsvitamin Dcalcium preparationdietary guidancebone density

《中国食物与营养》 2026 (4)

186-189,4

西安市科技计划项目[项目编号:20YXYJ0006(2)].

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