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从酸枣仁的药食同源价值角度论其对抑郁症的作用OA

From the perspective of food and medicine homology:the effects of Suanzaoren(Ziziphi Spinosae Semen)on depression

中文摘要英文摘要

抑郁症具有患病率高、复发率高的特点,传统抗抑郁药物存在不良反应及疗效不稳定等问题.药食同源类药材为抑郁症的防治提供了新的方向.其中,酸枣仁的相关研究兼具学术与应用价值.本文以药食同源理论为核心,梳理酸枣仁防治抑郁症的中医理论与实践依据,探讨酸枣仁在临床干预与保健食品开发中的应用价值.酸枣仁的中医功效与郁证的核心病机高度契合,其黄酮、皂苷等活性成分可通过调节神经递质、抑制中枢神经炎症反应等机制发挥抗抑郁作用,药食两用的特性使得酸枣仁在抑郁症治疗及大健康产业开发中具有良好的应用前景.

Depression is characterized by high prevalence and recurrence rates.Conventional antidepressants are associated with adverse reactions and inconsistent efficacy,whereas food and medicine homologous substances offer a novel approach to the prevention and treatment of depression.Among these,research on Suanzaoren(Ziziphi Spinosae Semen)is of both academic significance and practical value.Based on the theory of food and medicine homology,this article systematically reviews the Chinese medicine theoretical basis and practical evidence supporting the use of Suanzaoren(Ziziphi Spinosae Semen)for the prevention and treatment of depression,and further examines its application value in clinical intervention and functional food development.The Chinese medicine actions of Suanzaoren(Ziziphi Spinosae Semen)closely correspond to the core pathogenesis of depression.Its active constituents,including flavonoids and saponins,may exert antidepressant effects through mechanisms such as modulation of neurotransmitters and inhibition of inflammatory responses in the central nervous system.Owing to its dual use as both a medicinal substance and a food ingredient,Suanzaoren(Ziziphi Spinosae Semen)shows promising prospects for application in the treatment of depression and in the development of the health and wellness industry.

郑书维;李芊;杨萍

湖南中医药大学,湖南 长沙 410208||湖南省第二人民医院(湖南省脑科医院),湖南 长沙 410007湖南中医药大学,湖南 长沙 410208||湖南省第二人民医院(湖南省脑科医院),湖南 长沙 410007湖南中医药大学,湖南 长沙 410208||湖南省第二人民医院(湖南省脑科医院),湖南 长沙 410007

医药卫生

酸枣仁抑郁症药食同源

Suanzaoren(Ziziphi Spinosae Semen)depressionfood and medicine homology

《药食同源杂志》 2026 (2)

86-92,7

湖南省精神行为障碍中西医结合防治临床研究中心课题(2023SK2040).

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