超声生物显微镜眼前段参数测量的标准化与规范化OA
A review of the standardization and normalization of anterior segment parameter measurement using ultrasound biomicroscopy
超声生物显微镜(ultrasound biomicroscope,UBM)凭借高频超声(50~100 MHz)的特性突破了光学检查的局限,成为眼前段结构测量评估的重要工具,广泛应用于角膜病、青光眼、白内障、眼外伤、屈光手术等多个领域.但是,目前 UBM 参数测量仍然存在许多问题:参数标准化缺失导致同一参数的命名不同,或同一命名但定义不相同;测量方法不规范导致不同研究的对比性差;图像质量标准不够详细规范影响测量的准确性.这些问题影响了测量的精准性,也制约了多中心研究和数据互认.为此,本综述系统地梳理了角膜、前房、房角、虹膜、后房、晶状体及悬韧带、睫状体等 UBM 参数的标准测量方法,并归纳不同文献中的参数定义矛盾.分析测量误差的因素:声速设定与实际速度的偏差、接触式操作对眼球的干扰、操作者经验差异及与其他设备测量的客观差异等.在这个基础上,我们提出了改进方法:制定规范的检查流程、明确参数定义和测量方法、建立分场景图像质量标准及统一的设备校准方案.将来,UBM 参数测量将借助人工智能(artificial intelligence,AI)实现参数自动测量,结合三维成像技术、多普勒技术提升参数的全面性,向智能化和多维化发展,为眼科精准诊疗提供更全面的支持.
The ultrasound biomicroscope(UBM),leveraging the characteristics of high-frequency ultrasound(50-100 MHz),has overcome the limitations of optical examinations and emerged as a crucial tool for measuring and evaluating anterior segment structures.It is widely applied in various fields,including corneal diseases,glaucoma,cataracts,ocular trauma,and refractive surgery.However,several issues persist in current UBM parameter measurements:the lack of parameter standardization results in different names for the same parameter or inconsistent definitions for parameters with the same name;non-standardized measurement methods lead to poor comparability across different studies;and inadequate and non-detailed image quality standards affect measurement accuracy.These problems undermine the precision of measurements and constrain multi-center research and data interoperability.To address these challenges,this review systematically outlines standardized measurement methods for UBM parameters related to the cornea,anterior chamber,anterior chamber angle,iris,posterior chamber,lens and zonular fibers,and ciliary body.It also summarizes contradictions in parameter definitions across different studies.Furthermore,factors contributing to measurement errors are analyzed,including discrepancies between the assumed and actual sound velocities,interference from contact-based operation on the eyeball,variations in operator experience,and objective differences compared to measurements from other devices.Building on this analysis,we propose improvement strategies,such as establishing standardized examination protocols,clarifying parameter definitions and measurement methods,developing scenario-specific image quality standards,and implementing unified device calibration schemes.In the future,UBM parameter measurement is expected to achieve automated parameter measurement with the aid of artificial intelligence(AI).By integrating three-dimensional imaging technology and Doppler techniques,it will enhance the comprehensiveness of parameters and evolve toward intelligence and multi-dimensionality,providing more holistic support for precision ophthalmic diagnosis and treatment.
陈立明;肖辉;叶一明;蔡小于;杨扬帆
中山大学中山眼科中心,眼病防治全国重点实验室,广东省眼科视觉科学重点实验室,广州 510060中山大学中山眼科中心,眼病防治全国重点实验室,广东省眼科视觉科学重点实验室,广州 510060中山大学中山眼科中心,眼病防治全国重点实验室,广东省眼科视觉科学重点实验室,广州 510060中山大学中山眼科中心,眼病防治全国重点实验室,广东省眼科视觉科学重点实验室,广州 510060中山大学中山眼科中心,眼病防治全国重点实验室,广东省眼科视觉科学重点实验室,广州 510060
医药卫生
超声生物显微镜眼前节参数测量标准化人工智能
ultrasound biomicroscopeanterior segmentparameter measurementstandardizationartificial intelligence
《眼科学报》 2026 (4)
313-324,12
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