基于NHANES数据分析相对脂肪量与超重、肥胖成年女性压力性尿失禁的关系OA

Objective Exploring the association between relative fat mass(RFM)and stress urinary incontinence(SUI)in overweight and obese adult women based on the National Health and Nutrition Examination Survey(NHANES).Methods Using data from the 2011-2018 NHANES,a cross-sectional analysis was conducted on 6 190 overweight or obese women aged ≥ 20 years.The RFM was calculated based on the participants' height and waist circumference.The history of SUI was obtained through self-reports.The participants were divided into four groups according to the quartiles(QI-Q4)of RFM values.Weighted logistic regression analysis,smoothing curve fitting,and subgroup analysis were used to investigate the relationship between RFM and SUI.Results A total of 6 190 participants were included in this study,of whom 2 746(47.18％)had SUI.Weighted logistic regression analysis revealed that,in the fully adjusted model(model 3),RFM was independently associated with the risk of SUI(OR=1.06,95％CI:1.03-1.08,P=0.0004).Smoothing curve fitting indicated that RFM was positively linearly associated with the risk of SUI,meaning that,as RFM increased,the risk of SUI increased too.Subgroup analysis revealed that there was an interaction between RFM and SUI in relation to a history of depression(P for interaction＜0.05).Conclusion Among overweight and obese adult women in the United States,higher levels of RFM are associated with an increased risk of SUI.RFM has the potential to serve as a biomarker for assessing the risk of SUI.Given that obesity is also a risk factor for SUI in Chinese women,this finding may inform SUI risk prediction in similar Chinese populations;however,its applicability requires further validation.