基于抗凝管理平台的延续性抗凝管理在心脏瓣膜置换术后患者中的应用OA
Application of continuous anticoagulation management based on anticoagulation management platform in patients after heart valve replacement
目的 探讨基于抗凝管理平台的延续性抗凝管理在心脏瓣膜置换术后患者中的应用效果.方法 选取2021年5月—2023年5月在心脏瓣膜置换术后接受华法林抗凝的60例患者,按随机数字表法分为对照组(n=30)、研究组(n=30).对照组给予常规抗凝管理,研究组在对照组基础上实施基于抗凝管理平台的延续性抗凝管理.比较两组抗凝知识掌握度、国际标准化比值(INR)达标率、治疗依从性、生活质量[欧洲五维生存质量量表(EQ-5D)评分]及并发症发生率.结果 术后3个月研究组INR达标率为96.67%(29/30),与对照组的83.33%(25/30)比较差异无统计学意义(P>0.05).干预1年后,研究组抗凝知识掌握度、治疗依从性各方面评分以及总分均高于对照组(P<0.05).干预1年后,研究组EQ-5D各维度评分以及总分低于对照组(P<0.05).两组干预期间并发症总发生率比较差异无统计学意义(P>0.05).结论 基于抗凝管理平台的延续性抗凝管理可提升心脏瓣膜置换术后患者华法林抗凝治疗依从性,提高INR达标率及抗凝知识掌握度,并改善其生活质量.
Objective To investigate the application effect of continuous anticoagulation management based on the anticoagulation management platform in patients after cardiac valve replacement surgery.Methods Sixty patients who underwent heart valve replacement surgery and received Warfarin anticoagulation therapy from May 2021 to May 2023 were selected and divided into a control group(n=30)and a study group(n=30)according to the random number table method.The control group received conventional anticoagulation management,while the study group received continuous anticoagulation management based on the anticoagulation management platform on the basis of the control group.The mastery of anticoagulation knowledge,the rate of achieving therapeutic international normalized ratio(INR)range(INR achievement rate),treatment compliance,quality of life[European Five-Dimensional Quality of Life Scale(EQ-5D)score],and the incidence of complications were compared between the two groups.Results At 3 months after the surgery,the INR achievement rate in the study group was 96.67%(29/30),which showed no significant difference compared with the 83.33%(25/30)in the control group(P>0.05).At 1 year after the intervention,the study group scored higher than the control group in terms of anticoagulation knowledge mastery,treatment compliance,and overall score(P<0.05).At 1 year after the intervention,the EQ-5D scores of each dimension and the total score of the study group were lower than those of the control group(P<0.05).There was no significant difference in the total incidence of complications between the two groups during the intervention period(P>0.05).Conclusion Continuous anticoagulation management based on the anticoagulation management platform can enhance the compliance of patients after cardiac valve replacement with Warfarin anticoagulation therapy,increase the INR achievement rate,improve their mastery of anticoagulation knowledge,and enhance their quality of life.
史俊康;孔令才;姜峰;宣建宗
仪征市人民医院心血管内科,江苏仪征 211400仪征市人民医院心血管内科,江苏仪征 211400仪征市人民医院心血管内科,江苏仪征 211400天长市中医院中医内科,安徽天长 239000
心脏瓣膜病抗凝管理平台延续性抗凝管理心脏瓣膜置换术华法林依从性
valvular heart diseaseanticoagulation management platformcontinuous anticoagulation managementheart valve replacementWarfarincompliance
《临床误诊误治》 2026 (9)
28-34,7
2023年度安徽省中医药传承创新科研项目(2023CCZC27)扬州大学心脏大血管病研究院开放课题(YIHV0007)
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