经口腔前庭入路与经腋窝入路机器人辅助甲状腺癌根治术对颈部淋巴结清扫及喉返神经保护的对比研究OA
A comparative study of robot-assisted radical thyroidectomy via transoral vestibular approach versus transaxillary approach on cervical lymph node dissection and recurrent laryngeal nerve protection
目的:探究经口腔前庭入路与经腋窝入路机器人辅助甲状腺癌根治术对颈部淋巴结清扫及喉返神经保护效果的影响.方法:回顾性分析2021年5月—2024年11月于空军军医大学唐都医院接受机器人辅助甲状腺癌根治术的120例患者临床资料,按手术入路分为TOVA组(n=68,经口腔前庭入路)和TAA组(n=52,经腋窝入路).采用倾向评分匹配(PSM)按1∶1匹配后,两组各纳入50例.比较两组患者的手术相关指标、术后疼痛程度、声带功能、吞咽功能及术后并发症发生率.结果:TAA组手术时间短于TOVA组(P<0.05);两组住院时间、术中出血量及淋巴结清扫数目比较,差异无统计学意义(P>0.05).术后6h及12 h,TAA组视觉模拟评分法(VAS)评分均低于TOVA组(P<0.05).术后1个月,两组谐波噪声比升高,振幅微扰、基频微扰、基频均降低,且TOVA组谐波噪声比更高,振幅微扰、基频微扰、基频更低(P<0.05).术后1个月,TOVA组安德森吞咽困难量表(MDADI)总分高于TAA组(P<0.05).术后1个月,两组并发症总发生率比较,差异无统计学意义(P>0.05).结论:经口腔前庭入路与经腋窝入路对机器人辅助甲状腺癌根治术患者均具有较好的治疗效果,两种入路均可有效清除淋巴结.其中,经腋窝入路手术时间更短、术后疼痛更轻,经口腔前庭入路对喉返神经的损伤更轻.临床实践中,应根据患者的具体情况选择合适的手术入路.
Objective:To compare the effect of transoral vestibular approach(TOVA)and transaxillary approach(TAA)on cervical lymph node dissection and recurrent laryngeal nerve(RLN)protection in robot-assisted radical thyroidectomy for thyroid cancer.Methods:Clinical data of 120 patients who underwent robot-assisted radical thyroidectomy at Tangdu Hospital,Fourth Military Medical University from May 2021 and November 2024 were retrospectively analyzed.Patients were divided into the TOVA group(n=68)and the TAA group(n=52)according to the surgical approach.After propensity score matching(PSM)at a 1∶1 ratio,50 patients were included in each group.Surgical parameters,postoperative pain levels,vocal cord function,swallowing function,and complication rates were compared between the two groups.Results:The TAA group had a significantly shorter operative time than the TOVA group(P<0.05).No statistically significant differences were observed between the two groups in terms of length of hospital stay,intraoperative blood loss,or number of lymph nodes dissected(P>0.05).At 6 h and 12 h after surgery,the TAA group showed lower visual analog scale(VAS)scores than the TOVA group(P<0.05).At 1 month after surgery,both groups showed increased harmonic noise ratio(HNR)and decreased jitter,shimmer,and fundamental frequency.However,the TOVA group had a higher HNR and lower jitter,shimmer and fundamental frequency than the TAA group(P<0.05).At 1 month after surgery,the TOVA group had a higher total score on the M.D.Anderson dysphagia inventory(MDADI)than the TAA group(P<0.05).The overall complication rate at 1 month after surgery was not significantly different between the two groups(P>0.05).Conclusion:Both TOVA and TAA are effective approaches for robot-assisted radical thyroidectomy,with comparable lymph node dissection efficacy.TAA is associated with shorter operative time and less postoperative pain,while TOVA results in less impairment to the RLN.In clinical practices,the operative approach should be selected based on patients' specific conditions.
陈娜娜;曹莉莉;王娟;屈雪纯
空军军医大学唐都医院麻醉手术科 陕西西安 710038空军军医大学唐都医院麻醉手术科 陕西西安 710038空军军医大学唐都医院麻醉手术科 陕西西安 710038空军军医大学唐都医院麻醉手术科 陕西西安 710038
医药卫生
手术机器人口腔前庭入路腋窝入路甲状腺癌淋巴结清扫数目喉返神经
Surgical RobotTransoral Vestibular ApproachTransaxillary ApproachThyroid CancerNumber of Lymph Node DissectionRecurrent Laryngeal Nerve
《机器人外科学杂志(中英文)》 2026 (4)
612-618,7
国家自然科学基金(8200101858) National Natural Science Foundation of China(8200101858)
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