Factor Ⅷ restores bone parameters and modulates muscle proteo-metabolome in Factor Ⅷ knockout male miceOA
Factor Ⅷ restores bone parameters and modulates muscle proteo-metabolome in Factor Ⅷ knockout male mice
Antoine Babuty;Oleksandr Boychenko;Marie-Françoise Heymann;Dominique Heymann;Javier Muñoz-Garcia;Olivier D.Christophe;Laurie Fradet;Manon Taupin;Denis Cochonneau;Emilie Ollivier;Frank Driessler;Claudia Lange
Nantes University Hospital,Department of Hemostasis,Nantes,France||Nantes Université,CNRS,UMR6286,US2B,2 Rue de la Houssinière,44322 Nantes,France||Institut de Cancérologie de l'Ouest,Heterogeneity and Precision Medicine laboratory,Blvd Jacques Monod,44805 Saint-Herblain,FranceBayer AG,Translational Sciences/Omics Research,Wuppertal,GermanyNantes Université,CNRS,UMR6286,US2B,2 Rue de la Houssinière,44322 Nantes,France||Institut de Cancérologie de l'Ouest,Heterogeneity and Precision Medicine laboratory,Blvd Jacques Monod,44805 Saint-Herblain,France||Institut de Cancérologie de l'Ouest,Pathology Research Platform,Saint-Herblain,FranceNantes Université,CNRS,UMR6286,US2B,2 Rue de la Houssinière,44322 Nantes,France||Institut de Cancérologie de l'Ouest,Heterogeneity and Precision Medicine laboratory,Blvd Jacques Monod,44805 Saint-Herblain,France||University of Sheffield,School of Medicine and Population Health,Sheffield,UKNantes Université,CNRS,UMR6286,US2B,2 Rue de la Houssinière,44322 Nantes,France||Institut de Cancérologie de l'Ouest,Heterogeneity and Precision Medicine laboratory,Blvd Jacques Monod,44805 Saint-Herblain,FranceINSERM,Université Paris-Saclay,U1176,Paris,FranceNantes Université,CNRS,UMR6286,US2B,2 Rue de la Houssinière,44322 Nantes,France||Institut de Cancérologie de l'Ouest,Heterogeneity and Precision Medicine laboratory,Blvd Jacques Monod,44805 Saint-Herblain,FranceInstitut de Cancérologie de l'Ouest,Pathology Research Platform,Saint-Herblain,FranceInstitut de Cancérologie de l'Ouest,Heterogeneity and Precision Medicine laboratory,Blvd Jacques Monod,44805 Saint-Herblain,FranceInstitut de Cancérologie de l'Ouest,Heterogeneity and Precision Medicine laboratory,Blvd Jacques Monod,44805 Saint-Herblain,FranceBayer Consumer Care AG,TA Medical Affairs Hematology,Basel,SwitzerlandBayer AG,Precision Medicine Markers,Berlin,Germany
《骨研究（英文版）》 2026 (2)
507-523,17
Medical writing for this manuscript was assisted by MPIYP(MC Béné),Paris,France.The authors would like to thank Alicia Grunow and Christian Schultewolter,Bayer AG,for LC-MS proteomics and metabolomics analysis.Authors would also want to acknowledge the IBISA MicroPICell facility(Biogenouest),a member of the national infrastructure France-Bioimaging supported by the French National Research Agency(ANR-10-INBS-04).
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