功能性近红外光谱技术在失眠障碍中的应用进展OA

The prevalence rate of insomnia is as high as 15％,presents limitations in traditional diagnostic methods for both mechanistic research and clinical assessment.Functional near-infrared spectroscopy(fNIRS)is an emerging non-invasive neural monitoring technique.fNIRS possesses the capability for direct monitoring of cerebral cortical haemodynamics,featuring a sampling rate of approximately 10Hz or higher and excellent resistance to motion artefacts.fNIRS has become an important tool for investigating the neural mechanisms of insomnia and for clinical monitoring.fNIRS can effectively monitor dynamic changes in oxyhaemoglobin levels within superficial cortical regions such as the prefrontal cortex in insomnia patients,as well as alterations in the connectivity state of the default mode network between certain cortical regions.fNIRS provides novel data supporting the exploration of neural circuit mechanisms underlying sleep-wake regulation.The combined application of fNIRS and multimodal technologies demonstrates potential for guiding personalised treatment.This paper systematically reviews the technical advantages and research progress of fNIRS in assessing brain function and monitoring treatment efficacy for insomnia disorders,aiming to advance the application of fNIRS in clinical research and facilitate the development of more precise objective assessment and intervention strategies for insomnia.