Oligodendrocyte ferroptosis:Novel mechanisms in multiple sclerosisOA
Myelination in the central nervous system(CNS)is a highly intricate process,exclusive to vertebrates,that relies on the coordinated interaction between oligodendrocytes(OLs)and neurons.In addition to their role in forming myelin,accumulating evidence indicates that OLs provide crucial trophic support to axons,contributing to normal CNS function.Notably,OL injury and loss are observed in a variety of human conditions,including stroke,traumatic injuries of the brain and spinal cord,as well as neurodegenerative disorders such as multiple sclerosis(MS).
Valentina Saverio;Dmitry Lim;Marco Corazzari
Department of Health Sciences,School of Medicine,Center for Translational Research on Autoimmune and Allergic Disease(CAAD),University of Piemonte Orientale,Novara,Italy Department of Pharmaceutical Sciences,University of Piemonte Orientale,Novara,ItalyDepartment of Pharmaceutical Sciences,University of Piemonte Orientale,Novara,ItalyDepartment of Health Sciences,School of Medicine,Center for Translational Research on Autoimmune and Allergic Disease(CAAD),University of Piemonte Orientale,Novara,Italy
医药卫生
central nervous systemcentral nervous system cnsferroptosisoligodendrocytemyelinationmultiple sclerosisvertebratestrophic support
《Neural Regeneration Research》 2026 (8)
P.3561-3562,2
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