肺络病证治视角下慢性阻塞性肺疾病的证治规律OA
Syndrome Differentiation and Treatment Patterns in Chronic Obstructive Pulmonary Disease Guided by the Theory of Lung Collateral Disease
基于肺络病证治理论,探讨慢性阻塞性肺疾病(COPD)"气络-气道-血(脉)络"的传变规律.肺之气络承载元气、宗气、卫气,主调控与温养;肺之气道为气机升降之通道;肺之血(脉)络运行营血以濡养渗灌.三者协同配合,共同完成肺主气、司呼吸及"换气转血"的核心功能,其功能交汇于"孙络-玄府".COPD的发生发展遵循"气络-气道-血(脉)络"的传变规律,即初期以气络因虚留滞(宗气虚陷)为本,进而导致气道壅滞不利、气道绌急;终则气病及血,形成"痰挟瘀血碍气而病"的脉络瘀阻状态.在此过程中,病理损伤具有交互性.据此提出COPD"心肺气虚,脉络瘀阻,气道壅滞"的核心病机,并确立益气活血通络、化痰止咳定喘的治法,为临床精准辨治提供理论依据.
This paper explores the transmission patterns of"qi collaterals-qi airways-blood(vessels)collaterals"in chronic obstructive pulmonary disease(COPD)based on the syndrome differentiation and treatment theory of lung collateral disease.Lung qi collaterals carry original qi,pectoral qi and defensive qi,primarily responsible for regula-tion and nourishment.The lung's airway serves as the pathway for the ascending and descending of qi.The lung's blood(vessel)collaterals circulate ying(营)-blood to nourish and infiltrate.Those three work synergistically to com-plete the core function of the lung,including governing qi,controlling respiration,and facilitating"qi exchange and blood transformation",with their functions converging in the"minute collateral-sweat pores".The occurrence and de-velopment of COPD follow the transmission pattern of"qi collaterals-qi airways-blood(vessels)collaterals".Initially,the condition is rooted in qi stagnation caused by deficiency(pectoral qi deficiency and sink),which leads to airway obstruction and difficulty in ventilation.Ultimately,disorder of qi affects the function of blood,resulting in a state of vessel collaterals obstruction characterized as"phlegm complicated by blood stasis hindering qi causes disease".
贾振华
山东中医药大学药物研究院,山东省济南市长清区大学科技园大学路4655号,250355||络病理论创新转化全国重点实验室||河北以岭医院
慢性阻塞性肺疾病肺络病气络血络心肺气虚活血通络
chronic obstructive pulmonary diseaselung collateral diseaseqi collateralsblood collateralsqi defi-ciency of the heart and lungpromote blood circulation and unblock collaterals
《中医杂志》 2026 (7)
736-740,5
山东省科学技术厅国家级领军人才配套支持项目(2025GJJLJRC-112)国家中医药管理局中医药创新团队及人才支持计划(ZYYCXTD-D-202206)河北省科学技术厅高水平人才团队建设专项(253A7702D)河北省科技研发平台专项(24462501D)河北省创新能力提升计划(24462501D)
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