2 474例食管鳞状细胞癌患者先天运气与后天发病关联性研究OA
Study on the Correlation Between Congenital Circuit-Qi and the Onset of Acquired Disease in 2 474 Patients with Esophageal Squamous Cell Carcinoma
目的 基于五运六气理论,分析食管鳞状细胞癌患者先天运气特征与其后天发病的关联性,为食管鳞癌的防治提供新的思路和理论依据.方法 通过回顾性研究的方法,选取本团队建立的食管癌病案库收治的2 474例食管鳞癌患者,运用SPSS 27.0 统计软件,统计分析患者出生时间所对应的五运六气各要素分布情况,并归纳其先天运气禀赋特征.结果 食管鳞癌患者出生日期乙、癸天干居多,地支多为卯;岁运金运不及、火运不及较为常见;主气和客气中,阳明燥金、太阴湿土、少阳相火占比偏高;司天在泉中,阳明燥金司天-少阴君火在泉的组合突出.且其分布差异均有统计学意义(P＜0.05).结论 食管鳞癌患者的后天发病与先天运气之间有一定的关联性,出生于特定不利运气相合年份的患者比例较高.基于此,提出"抑金运、调相火、化湿浊"等治则,从肺、肝论治,辅以清热润燥、化痰祛瘀之法,为食管鳞癌的防治提供具有潜在应用价值的新思路.
Objective:Based on the theory of five circuits and six qi,this study aims to analyze the correlation between congenital circuit-qi characteristics of patients with esophageal squamous cell carcinoma and the onset of their acquired disease,so as to provide new ideas and theoretical basis for the prevention and treatment of esophageal squamous cell carcinoma.Methods Using a retrospective study,2 474 patients with esophageal squamous cell carcinoma enrolled in the esophageal cancer medical record database established by our team were selected.The SPSS 27.0 statistical software was used to analyze the distribution of various elements of five circuits and six qi corresponding to the patients'birth times,and to summarize the endowment characteristics of their congenital circuit-qi.Results Among patients with esophageal squamous cell carcinoma,the birth dates showed a predominance of the heavenly stems Yi and Gui and the earthly branch Mao.Deficiency of yearly circuit of Metal and Fire were relatively common.Among the primary qi and secondary qi,Yangming Zaojin,Taiyin Shitu,and Shaoyang Xianghuo accounted for high proportions.Regarding celestial and terrestrial managements,the combination of Yangming Zaojin as celestial management and Shaoyin Junhuo as terrestrial management was predominant,with the differences in their distributions were statistically significant(P＜0.05).Conclusion There is a certain correlation between the acquired onset of esophageal squamous cell carcinoma and the congenital circuit-qi,and a high proportion of patients are born in years with specific unfavorable circuit-qi combinations.Based on this,treatment principles such as"suppressing the Metal circuit,regulating the ministerial fire,and resolving dampness-turbidity"are proposed.The treatment focuses on lung and liver,supplemented by methods of clearing heat,moistening dryness,resolving phlegm,and removing blood stasis,providing new ideas with potential application value for the prevention and treatment of esophageal squamous cell carcinoma.
冯非凡;郑玉玲;张亚玲;张呈伟;张梦瑶;郑佳林;陈晓琦
河南中医药大学第一附属医院脾胃肝胆科,河南 郑州 450000||河南中医药大学第一临床医学院,河南 郑州 450000河南中医药大学第一附属医院血液肿瘤科,河南 郑州 450000河南中医药大学第一附属医院血液肿瘤科,河南 郑州 450000河南中医药大学第一附属医院脾胃肝胆科,河南 郑州 450000||河南中医药大学第一临床医学院,河南 郑州 450000河南中医药大学第一附属医院脾胃肝胆科,河南 郑州 450000||河南中医药大学第一临床医学院,河南 郑州 450000河南中医药大学第一附属医院脾胃肝胆科,河南 郑州 450000||河南中医药大学第一临床医学院,河南 郑州 450000河南中医药大学第一附属医院血液肿瘤科,河南 郑州 450000
医药卫生
食管鳞状细胞癌五运六气运气禀赋出生日期发病规律防治思路
esophageal squamous cell carcinomafive circuits and six qicircuit endowmentbirth dateonset patternprevention and treatment approach
《中医肿瘤学杂志》 2026 (2)
95-103,9
河南省省级科技研发计划联合基金(优势学科培育类)项目(编号:242301420084)河南省卫生健康委国家中医药传承创新中心科研专项目(编号:2023ZXZX1056)中西医防治重大疾病河南省协同创新中心(编号:教科技[2023]413号)。
评论