重复低强度红光控制近视的研究进展OA

In recent years,repeated low-level red light therapy(RLRL),as an emerging intervention method for myopia,has demonstrated significant effects in delaying the elongation of the eye axis and the increase in refractive power.A large number of clinical studies have confirmed that its efficacy is superior to that of atropine and corneal reshaping len-ses.However,the mechanism of action and long-term safety of RLRL remain unclear.Basic research indicates that RLRL may control the progression of myopia through various pathways such as utilizing the longitudinal chromatic aberration principle,regulating the secretion of dopamine in the retina,increasing the thickness and blood perfusion of the choroid,improving scleral hypoxia,reducing inflammation and oxidative stress responses.In terms of safety,most studies have shown good short-term safety,but the latest high-resolution imaging studies suggest a potential risk of reduced cone cell density in the retina and a rebound effect after discontinuation.This article reviews the mechanism of action,clinical effec-tiveness and safety of RLRL in controlling myopia,with the aim of providing a reference for clinical application.