基于"阳化气,阴成形"理论探讨缺血性脑卒中后睡眠障碍病机与治疗OA
Exploration of the pathogenesis and treatment of sleep disorders after ischemic stroke based on the theory of"Yang transforming Qi and Yin consitituting form"
睡眠障碍是缺血性脑卒中临床常见并发症,具有高发病率、高复发率等特点,核心临床表现为入睡困难与睡眠维持障碍,部分患者还可伴随日间嗜睡、精神萎靡等症状.近年来,随着缺血性脑卒中发病率逐年攀升,其继发睡眠障碍的患病率亦呈显著升高趋势,不仅严重阻碍患者神经功能恢复,延缓肢体运动、语言等功能康复,还会损害患者身心健康,诱发焦虑、抑郁等不良情绪,降低患者生活质量,增加再发脑卒中风险,已成为影响卒中患者预后的重要因素.文章基于《黄帝内经》中"阳化气,阴成形"理论,结合缺血性脑卒中后睡眠障碍的临床特征与病理演变,提出其病机核心在于"阳化气,阴成形"功能失衡,营卫气血失调,最终导致心脑形神难安.其中,阳化气不及与阴成形太过所致的清阳不升、痰瘀阻窍是疾病发病基础,阳化气太过与阴成形不足所致的气火有余、津亏血弱是疾病演变与难愈的关键.基于中医学"整体观念"与"辨证论治"原则,认为防治缺血性脑卒中后睡眠障碍需以调和阴阳、恢复"化气"与"成形"平衡为根本治则,并提出"温通并用,调和气化,化痰除湿,活血解毒,解郁清热,滋阴养血"之法,通过联合治疗恢复阴阳平衡,实现阳气宣通、阴霾消散、瘀浊清除、阴液复充,最终使心脑安和、形神俱宁.
Sleep disorders are common clinical complications of ischemic stroke,characterized by high incidence and high recurrence rate.The core clinical manifestations are difficulty falling asleep and sleep maintenance insomnia.Some patients may also be accompanied by symptoms such as daytime sleepiness and listlessness.In recent years,with the increasing incidence of ischemic stroke year by year,the prevalence of secondary sleep disorders has also shown a significant upward trend.This not only seriously hinders the recovery process of patients'neurological functions,delays the rehabilitation of limb movement,language and other functions,but also harms the physical and mental health of patients,induces negative emotions such as anxiety and depression,reduces the quality of life,and increases the risk of restroke.It has become an important factor influencing the prognosis of stroke patients.Based on the theory of"Yang(阳)transforming Qi(气)and Yin(阴)constituting form"in Huangdi Neijing(《黄帝内经》),and combined with the clinical features and pathological evolution of sleep disorders after ischemic stroke,this article proposes that the core pathogenesis lies in the functional imbalance of"Yang transforming Qi and Yin constituting form",along with the disharmony of Ying(营)Qi and Wei(卫)Qi and blood,ultimately leading to restlessness of the heart-brain-body and spirit.Among them,the failure of clear Yang to acsend and the blockage of the orifices by phlegm and blood stasis due to the insufficient transformation of Yang into Qi and the excessive formation of Yin-derived pathological products serve as the basis for the onset of the disease.Excessive Yang transforming of Qi and insufficient Yin constituting form,lead to an excess of Qi and fire,deficiency of body fluids and blood weakness,which are the key factors contributing to the disease evolution and difficulty in curing.Based on the principles of"holistic concept"and"syndrome differentiation and treatment"in traditional Chinese medicine,it is believed that the fundamental treatment for preventing and treating sleep disorders after ischemic stroke should be to harmonize Yin and Yang and restore the balance between"Qi transformation"and"form constitution".It also proposes the methods of combining warming and unblocking to harmonize Qi transformation,eliminating phlegm and dampness,promoting blood circulation and detoxification,relieving depression and clearing heat,nourishing Yin and enriching blood.Through combined treatment,the balance of Yin and Yang can be restored,thereby ensuring smooth flow of Yang Qi,the dispelling gloom,the eliminating stasis and turbidity,and replenishing Yin fluids,this leads to peace of mind and brain,as well as tranquility of both body and spirit.
黄蕊;吴云虎
安徽中医药大学第一临床医学院,安徽 合肥,230031安徽中医药大学第一附属医院,安徽 合肥,230031
医药卫生
缺血性脑卒中睡眠障碍阳化气,阴成形调和阴阳
Ischemic strokeSleep disordersYang transforming Qi and Yin constituting formRegulation of Yin and Yang
《中医临床研究》 2026 (8)
38-43,6
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