经肛全直肠系膜切除术在低位直肠癌保肛治疗中的价值再审视OA
Reassessment of the value of transanal total mesorectal excision in sphincter-preserving surgery for low rectal cancer
经肛全直肠系膜切除术(taTME)的出现为低位直肠癌保肛治疗提供了新思路.通过自下而上的操作路径显著增强盆腔深部解剖的可视化,为局部进展期"困难骨盆"患者提供了新的保肛选择.中国学者在该领域作出了系统性贡献:从技术引进到规范化推广,从参与国际研究到牵头全球首个taTME 与腹腔镜 TME 对比的Ⅲ期随机对照研究(taLaR),研究成果发表于《美国医学会杂志》,标志着中国在该领域从"技术跟随者"跃升为"规则制定者".文章梳理 taTME 的解剖学基础、技术演进、关键临床证据、并发症防治、学习曲线、功能保护及未来发展方向,以期为临床实践提供参考.
Transanal total mesorectal excision(taTME)offers a novel approach for sphincter preservation in low rectal cancer.By employing a reverse"down-to-up"operative trajectory;this technique significantly enhances visualization of deep pelvic anatomy;enabling sphincter preservation in select patients with challenging"difficult pelvis"conditions where traditional laparoscopic surgery may be inadequate.Chinese scholars have made systematic contributions to this field;spanning technology introduction;standardized promotion;international collaborative research;and leadership in the world's first phase Ⅲ randomized controlled trial comparing taTME with laparoscopic TME(the TaLaR study).The publication of these findings in the Journal of the American Medical Association(JAMA)marks China's transition from a"technology follower"to a"rule-setter"in this domain.This article systematically reviews the anatomical basis;technical evolution;key clinical evidence;complication prevention and management;learning curve;functional preservation;and future directions of taTME;aiming to provide references for clinical practice.
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210029 江苏 南京,南京医科大学第一附属医院 结直肠外科
低位直肠癌经肛全直肠系膜切除术保肛手术学习曲线功能保护并发症防治
Low rectal cancerTransanal total mesorectal excisionSphincter-preserving surgeryLearning curveFunctional preservationComplication prevention and management
《中国肿瘤外科杂志》 2026 (2)
158-164,7
国家自然科学基金面上项目(82172956)
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