基于GBD2023中国和全球老年慢性阻塞性肺疾病的疾病负担分析OA
Analysis of the disease burden of geriatric chronic obstructive pulmonary disease in China and globally based on GBD2023
目的 本研究旨在全面分析中国和全球老年慢性阻塞性肺疾病(chronic obstructive pulmonary disease,COPD)的疾病负担.方法 研究基于使用2023版全球疾病负担(Global Burden of Disease,GBD)数据库,分析1990年和2023年中国和全球COPD的疾病负担情况,并对≥65岁老年人群采取基于年龄和性别亚组的疾病负担及变化趋势分析.结果与1990年相比,2023年时,无论是中国还是全球,COPD的发病数、患病数、死亡数及伤残调整寿命年数均呈现上升趋势;COPD的年龄标准化发病率、年龄标准化患病率、年龄标准化死亡率和年龄标准化伤残调整寿命年数率均呈现下降趋势.基于老年人群的年龄亚组分析发现,随着年龄的增加,COPD的疾病负担在中国和全球均呈现出显著的上升趋势.基于老年人群的性别亚组分析显示,男性群体的COPD疾病负担略高于女性群体,但女性老年群体COPD的疾病负担加重,并与男性老年群体的COPD疾病负担差距存在缩小趋势.结论 中国和全球老年人群COPD疾病负担在整体趋势,年龄及性别多个层面存在显著差异,生活方式及人居环境的改善及公共卫生政策的制定对于改变这一现状具有重要意义.
Objective To comprehensively analyze the disease burden of chronic obstructive pulmonary disease(COPD)in the older population of China and globally.Methods Using data from the 2023 version of the Global Burden of Disease(GBD)database,the disease burden of COPD in China and globally for the years 1990 and 2023 was analyzed.Additionally,the disease burden and trend variations in older populations based on age and sex subgroups.Results The results showed that from 1990 to 2023,both China and the global population had an increasing trend in the incidence,prevalence,mortality,and disability-adjusted life years(DALYs)of COPD.However,the age-standardized incidence rate(ASIR),age-standardized prevalence rate(ASPR),age-standardized mortality rate(ASMR),and age-standardized DALY rate(ASDR)of COPD decreased in both China and globally.Age subgroup analysis revealed a significant increase in the disease burden of COPD with advancing age,both in China and globally.Gender subgroup analysis demonstrated that the disease burden of COPD was slightly higher in males than in females.However,from 1990 to 2023,the disease burden in older women gradually increased and the gap between the disease burden in older males and females narrowed.Conclusions The burden of COPD among the older population in China and globally exhibits significant variation across overall trends,age groups,and genders.Improvements in lifestyle,living conditions,and the formulation of public health policies are of paramount importance in addressing this issue and altering the current trajectory.
周子一;岑颜;张允萁;石婧;崔佳;许小毛
北京医院 (国家老年医学中心)期刊编辑部,老年疾病国家临床医学研究中心,国家卫生健康委老年医学重点实验室,中国医学科学院老年医学研究院,北京 100730北京医院 (国家老年医学中心)期刊编辑部,老年疾病国家临床医学研究中心,国家卫生健康委老年医学重点实验室,中国医学科学院老年医学研究院,北京 100730华东理工大学生物工程学院,上海 200237北京医院 (国家老年医学中心)期刊编辑部,老年疾病国家临床医学研究中心,国家卫生健康委老年医学重点实验室,中国医学科学院老年医学研究院,北京 100730北京医院 (国家老年医学中心)呼吸与危重症医学科,老年疾病国家临床医学研究中心,国家卫生健康委老年医学重点实验室,中国医学科学院老年医学研究院,北京 100730北京医院 (国家老年医学中心)呼吸与危重症医学科,老年疾病国家临床医学研究中心,国家卫生健康委老年医学重点实验室,中国医学科学院老年医学研究院,北京 100730
老年人群慢性阻塞性肺疾病疾病负担
AgedChronic obstructive pulmonary diseaseDisease burden
《中国医学前沿杂志(电子版)》 2026 (2)
59-65,7
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