甘青乌头正丁醇部位苷类化学成分研究OA

In order to investigate the chemical constituents of glycosides in Aconitum tanguticum(Maxim.)Stapf,column chromatographic techniques such as silica gel,ODS,Sephadex LH-20,and semi-preparative high performance liquid chromatography were used to afford eight glycosides from the n-butanol fraction of the 85％ethanol extract of Aconitum tanguticum.Based on the physicochemical properties and spectral data,these compounds were identified as N-4-O-(β-D-glucopyranosyl)-phenethylbenzamide(1),N-(2′-β-D-glucopyranosyl-5′-methoxysalicyl)-4-hydroxy-3-methoxyanthranilic acid methyl ester(2),N-(2′-β-D-glucopyranosyl-5′-hydroxysalicyl)-4-hydroxy-3-methoxyanthranilic acid methyl ester(3),salidroside(4),benzyl primeveroside(5),phenethanol-β-D-xylose-(1″→6′)-β-D-glucopyranoside(6),4-dihydroxyphenethoxy-8-O-β-D-[6-O-(4-O-β-D-glucopyranosyl)-feruloyl]-glucopyranoside(7),phenethanol-α-L-arabinopyranosyl-(1″→6′)-β-D-glucopyranoside(8).Among them,compounds 1 and 2 were new compounds,and compounds 5,6,8 were isolated from Aconitum tanguticum for the first time.