多参数MRI对胃肠道间质瘤术前诊断的价值OA
Value of multi-parameter MRI in preoperative diagnosis of gastrointestinal stromal tumors
目的 探讨多参数磁共振成像(magnetic resonance imaging,MRI)对胃肠道间质瘤(gastro-intestinal stromal tumor,GIST)术前诊断的价值.方法 收集我院 2022 年 4 月~2025 年 4 月 80 例GIST 患者的临床资料.所有患者均接受 MRI 扫描,以手术病理结果为金标准,根据 2022 年版《NCCN肿瘤学临床实践指南》中 GIST 的危险度分级标准,将其分为低危组(n=24)、中危组(n=20)及高危组(n=36),分析各组 GIST 患者 MRI 特点,研究多参数 MRI 影像技术在 GIST 术前诊断中的价值.结果 GIST 不同危险度分组的 MRI 影像学特征有显著差异,包括肿瘤直径、部位、边界、形态、囊变坏死、转移、表观扩散系数(apparent diffusion coefficient,ADC)及强化方式(P<0.05).两两比较显示低危组与中、高危组之间,中危组与高危组之间均存在显著差异(P<0.05).经受试者工作特征(receiver operating char-acteristic,ROC)曲线分析,ADC 值联合动态增强的强化方式在 GIST 术前危险度分级预测中的曲线下面积(area under the curve,AUC)为0.985,灵敏度为94.06%,特异度为95.10%,联合诊断效能高于单一诊断.结论 MRI 在 GIST 术前评估中具有较高的价值,其征象与肿瘤的危险度密切相关.临床医生在诊断 GIST 时,应充分利用多参数 MRI,为患者提供更准确的诊断和治疗策略.
Objective To explore the value of multi-parameter magnetic resonance imaging(MRI)in the preoperative diagnosis of gastrointestinal stromal tumors(GIST).Methods A total of 80 GIST patients treated in our hospital from April 2022 to April 2025 were enrolled in this study.All patients underwent MRI scanning,with surgical pathological findings as the gold standard.According to the GIST risk stratification crite-ria in the 2022 edition of the NCCN Clinical Practice Guidelines in Oncology,the patients were divided into the low-risk group(n=24),intermediate-risk group(n=20),and high-risk group(n=36).The MRI features of GIST in each group were analyzed to evaluate the value of multi-parameter MRI in the preoperative diagnosis of GIST.Results Different risk stratification of GIST had significant differences in MRI features,including tumor diameter,location,boundary,morphology,cystic degeneration and necrosis,metastasis,apparent diffu-sion coefficient(ADC)and enhancement patterns(P<0.05).Pairwise comparisons revealed significant differ-ences between the low-risk group and the intermediate-/high-risk groups,as well as between the intermediate-risk group and high-risk group(P<0.05).Receiver operating characteristic(ROC)curve analysis showed that the area under the curve(AUC)of ADC value combined with the enhancement patterns of dynamic contrast-enhanced MRI in the preoperative risk prediction of GIST was 0.985,with a sensitivity of 94.06%and a specificity of 95.10%.The combined diagnostic efficacy was superior to that of single-index diagnosis.Conclusions MRI demonstrates high value in the preoperative evaluation of GIST,and its imaging findings are closely correlated with tumor risk stratification.Clinicians should make full use of multi-parameter MRI in the diagnosis of GIST to provide more accurate diagnosis and treatment strategies for patients.
韦小芳;罗春;肖恩华
长沙市第八医院,湖南 长沙 410100长沙市第八医院,湖南 长沙 410100中南大学湘雅二医院,湖南 长沙 410011
胃肠道间质瘤危险度分级磁共振表观扩散系数
gastrointestinal stromal tumorsrisk classificationmagnetic resonance imagingapparent diffusion coefficient
《中国现代手术学杂志》 2026 (1)
63-68,6
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