超声引导下尿道球囊扩张术对脊髓损伤后尿潴留的疗效研究OA

Objective:To evaluate the efficacy of ultrasound-guided urethral balloon dilation(UBD)in improving voiding function among patients with urinary retention after spinal cord injury(SCI).Methods:A randomized con-trolled trial with a Zelen design was conducted.A total of 74 inpatients with SCI-related urinary retention admitted were allocated 1∶1 to a intervention group or a control group.The intervention lasted 2 weeks.Primary outcomes were the neurogenic bladder symptom score(NBSS),voiding-diary measures and 10-item Connor-Davidson resili-ence scale(CD-RISC-10).Results:At baseline,there were no significant between-group differences in NBSS scores,mean daily catheterization frequency,or CD-RISC-10 scores.After 2 weeks of treatment,the intervention group demonstrated significant reductions in urinary storage and voiding symptom scores,outcome scores,total NBSS scores,and mean daily catheterization frequency(P<0.01),together with a significant increase in CD-RISC-10 scores(P<0.01).In the control group,mean daily catheterization frequency and outcome scores decreased signifi-cantly from baseline(P<0.01).Between-group comparisons at post-treatment showed that the intervention group achieved significantly better mean daily catheterization frequency,urinary storage and voiding symptom scores,total NBSS scores,and CD-RISC-10 scores than the control group(P<0.01,0.05).In addition,changes in CD-RISC-10 scores were significantly correlated with changes in mean daily catheterization frequency,urinary storage and voi-ding symptom scores,and total NBSS scores(P<0.01,0.05).Conclusion:Ultrasound-guided urethral balloon di-lation can,in the short term,improve storage and voiding symptoms and reduce the need for catheterization,while also enhancing patients'psychological resilience.The procedure is minimally invasive and feasible,and merits fur-ther clinical adoption and long-term follow-up evaluation.