身体质量指数对胰腺手术后手术部位感染影响的回顾性队列研究OA

Objective To explore the relationship between body mass index(BMI)and the risk of surgical site infection(SSI)after pancreatic surgery,and analyze the impact of BMI on SSI in different populations.Methods Patients who underwent pancreatic surgery at the First Affiliated Hospital with Nanjing Medical University from January 2022 to June 2023 were included for retrospective cohort study.Based on BMI,patients were divided into low weight group(BMI<18.5 kg/m2),normal weight group(18.5 kg/m2≤BMI<24 kg/m2),overweight group(24 kg/m2≤BMI<28 kg/m2),and obese group(BMI≥28 kg/m2).Impact of BMI on SSI was analyzed by logistic regression.Results A total of 1 345 patients were included in the analysis.Incidence of SSI after pancreatic surgery was 8.55%.Incidences of SSI in low weight group,normal weight group,overweight group,and obesity group were 3.57%,5.17%,12.36%,and 19.27%,respectively.Multivariate logistic analysis results showed that the risk of SSI occurrence in overweight group was 2.487 times of normal group(95%CI:1.570-3.939,P<0.001),and that in obese group was 5.353 times of normal group(95%CI:2.854-10.040,P<0.001).Subgroup analy-sis found that BMI had a more significant impact on the risk of SSI in individuals aged≥60 years old(interaction term P=0.009).Conclusion Elevated BMI significantly increases the risk of SSI in pancreatic surgery patients,and the impact is more obvious in the elderly population.It is recommended to incorporate BMI into preoperative infection risk assessment,together with the national"Weight management year"policy,to promote individualized weight management and precise infection prevention and control.