罗哌卡因椎管内麻醉联合芬太尼基础麻醉对痔切除患者麻醉效果观察OA
Clinical Observation of Anesthetic Efficacy of Ropivacaine Intraspinal Anesthesia Combined with Fen-tanyl Basal Anesthesia in Patients Undergoing Hemorrhoidectomy
目的:探讨罗哌卡因椎管内麻醉联合芬太尼基础麻醉对痔切除患者麻醉效果及安全性的影响.方法:采取前瞻性研究,选取2023年10月至2025年3月我院拟行痔切除术患者76例,将其随机分为观察组和对照组,每组38例.观察组患者采用罗哌卡因腰麻联合芬太尼静脉注射,对照组患者采用单纯罗哌卡因腰麻,比较2组患者不同时点血流动力学参数、视觉模拟量表(VAS)疼痛评分、麻醉效果、Ramsay评分以及不良反应发生情况.结果:2组患者麻醉后10 min(T1)、20 min(T2)、30 min(T3)时的心率(HR)、平均动脉压(MAP)均比麻醉前(T0)显著降低(P<0.05),2组组间比较差异无统计学意义(P>0.05).2组患者术毕即刻、术后0.5、2 h的VAS评分逐渐升高,术后6、12、24 h的VAS评分逐渐降低.观察组患者术后0.5、2、6 h的VAS评分均明显低于对照组(P<0.05).观察组患者感觉阻滞起效时间短于对照组,感觉阻滞持续时间长于对照组(P<0.05);2组患者运动阻滞起效、持续时间比较差异无统计学意义(P>0.05).2组患者Ramsay评分比较差异无统计学意义(P>0.05).2组患者围手术期不良反应发生率比较差异无统计学意义(P>0.05).结论:罗哌卡因椎管内麻醉联合芬太尼基础麻醉在痔切除术中能有效缩短感觉阻滞起效时间、延长镇痛持续时间,显著降低术后早期疼痛程度,且对血流动力学、运动阻滞及镇静深度无显著影响,安全性良好,优于单纯罗哌卡因腰麻方案.
Objective To investigate the anesthetic efficacy and safety of ropivacaine intraspinal anesthesia combined with fentanyl basal anesthesia in patients undergoing hemorrhoidectomy.Methods Total 76 patients scheduled to undergo hemorrhoidectomy at our hospital from October 2023 to March 2025 were enrolled in this prospective study and randomly divided into the observation group and the control group,with 38 cases in each group.The observation group received ropivacaine spinal anesthesia combined with intrave-nous fentanyl,while the control group received ropivacaine spinal anesthesia alone.Hemodynamic parameters,Visual Analogue Scale(VAS)pain score,anesthetic effect,Ramsay score and adverse reactions at different time points were compared between the two groups.Results Heart rate(HR)and mean arterial pressure(MAP)at 10 min(T1),20 min(T2)and 30 min(T3)after anesthesia were significantly lower than those before anesthesia(T0)in both groups(P<0.05),with no statistically significant differences between the two groups(P>0.05).The VAS scores of the two groups increased gradually immediately after operation,at 0.5 h and 2 h after operation,and decreased gradually at 6 h,12 h and 24 h after operation.The VAS scores of the observation group at 0.5 h,2 h and 6 h after operation were significantly lower than those of the control group(P<0.05).The onset time of sensory block in the observation group was shorter than that in the control group,and the duration of sensory block was longer(P<0.05).There were no significant differences in the onset time and duration of motor block between the two groups(P>0.05).There was no significant difference in Ramsay score between the two groups(P>0.05).There was no significant difference in the incidence of perioperative adverse reactions between the two groups(P>0.05).Conclusion Ropivacaine intraspinal anesthesia combined with fentanyl basal anesthesia can effectively shorten the onset time of sensory block,pro-long the duration of analgesia,and significantly reduce early postoperative pain in hemorrhoidectomy.It has no significant effect on hemodynamics,motor block and sedation depth,with good safety,which is superior to ropivacaine spinal anesthesia alone.
李园园;陶智慧
驻马店桐安肿瘤医院手术室(河南 驻马店 463000)驻马店桐安肿瘤医院手术室(河南 驻马店 463000)
痔切除术罗哌卡因芬太尼椎管内麻醉效果观察
Hemorrhoids hemorrhoidectomyRopivacaineFentanylIntraspinal anesthesiaClinical observation
《中国肛肠病杂志》 2026 (4)
50-53,4
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