经阴道超声、血清β-hCG联合检测对异位妊娠的诊断价值OA
Diagnostic Value of Transvaginal Ultrasound Combined with Serum β-hCG in Ectopic Pregnancy
目的 探讨经阴道超声、血清人绒毛膜促性腺激素(β-hCG)联合检测对异位妊娠的诊断价值.方法 回顾性选取2022年1月至2025年6月中牟县人民医院收治的121例疑似异位妊娠患者,以手术或病理结果为诊断"金标准",将其分为异位妊娠组(90 例)和非异位妊娠组(31 例).比较血清 β-hCG 水平,分析经阴道超声、血清 β-hCG 水平及联合检测对异位妊娠的诊断价值.结果 异位妊娠组血清β-hCG水平低于非异位妊娠组,差异有统计学意义(P<0.05);经阴道超声+血清 β-hCG 联合诊断异位妊娠的灵敏度为 95.56%,高于经阴道超声单独诊断(80.00%)和 β-hCG 单独诊断(77.78%),差异有统计学意义(P<0.05).结论 经阴道超声联合血清 β-hCG 检测可提高异位妊娠诊断的灵敏度、准确度及阴性预测值,降低漏诊率,但其特异度有所下降、误诊率有所升高,可能有助于提高初始筛查敏感性的辅助诊断方案.
Objective To investigate the diagnostic value of transvaginal ultrasound combined with serum human chorionic gonadotropin(β-hCG)in ectopic pregnancy.Methods A retrospective analysis was conducted on 121 patients with suspected ectopic pregnancy who were admitted to Zhongmu County People's Hospital from January 2022 to June 2025.Using surgical or pathological results as the diagnostic gold standard,the patients were divided into an ectopic pregnancy group(90 cases)and a non-ectopic pregnancy group(31 cases).Serum β-hCG levels were compared,and the diagnostic value of transvaginal ultrasound,serum β-hCG level,and their combined detection for ectopic pregnancy was analyzed.Results The serum β-hCG level in the ectopic pregnancy group was lower than that in the non-ectopic pregnancy group,and the difference was statistically significant(P<0.05).The sensitivity of transvaginal ultrasound combined with serum β-hCG for the diagnosis of ectopic pregnancy was 95.56%,which was higher than that of transvaginal ultrasound alone(80.00%)and β-hCG alone(77.78%),and the differences were statistically significant(P<0.05).Conclusion Transvaginal ultrasound combined with serum β-hCG detection can improve the sensitivity,accuracy,and negative predictive value for the diagnosis of ectopic pregnancy and reduce the missed diagnosis rate;however,its specificity decreases and its false-positive rate increases.This combined approach may be a useful auxiliary diagnostic strategy for improving the sensitivity of initial screening for ectopic pregnancy.
吴瑞红;蒋海旺;李永胜;李建
中牟县人民医院(中牟县人民医院总医院) 超声科,河南 郑州 451450中牟县人民医院(中牟县人民医院总医院) 超声科,河南 郑州 451450中牟县人民医院(中牟县人民医院总医院) 超声科,河南 郑州 451450中牟县人民医院(中牟县人民医院总医院) 超声科,河南 郑州 451450
异位妊娠经阴道超声人绒毛膜促性腺激素诊断价值
ectopic pregnancytransvaginal ultrasoundhuman chorionic gonadotropindiagnostic value
《临床研究》 2026 (4)
127-130,4
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