首页|期刊导航|医学信息|人工泪液联合普拉洛芬应用于白内障术后干眼症治疗中的效果及对患者视功能质量恢复的影响

人工泪液联合普拉洛芬应用于白内障术后干眼症治疗中的效果及对患者视功能质量恢复的影响OA

Effect of Artificial Tears Combined with Pranoprofen in the Treatment of Dry Eye After Cataract Surgery and its Impact on the Recovery of Visual Function Quality

中文摘要英文摘要

目的 分析白内障术后干眼症患者治疗中应用人工泪液联合普拉洛芬对其视功能质量恢复的影响.方法 研究对象为青海油田医院 2020 年 1 月-2024 年 12 月收治的白内障术后干眼症患者,共 260 例.利用随机数字表法分为两组(对照组与研究组),每组 130 例.对照组接受人工泪液治疗,研究组接受人工泪液治疗+普拉洛芬滴眼液治疗.对两组的临床疗效、干眼症状评分、泪液分泌指标改善情况[泪膜破裂时间(BUT)、角膜荧光素染色(FL)、泪液分泌试验(SⅠT)],以及视功能指标[负相对调节(NRA)、正相对调节(PRA)、调节灵敏度(AF)、调节幅度(AMP)、立体视]进行比较.结果 与对照组治疗总有效率的 75.38%比较,研究组更高,达 96.92%(P<0.05);与对照组治疗 2、4 周后干眼症状评分比较,研究组评分更低(P<0.05);同时,与对照组治疗后视功能指标比较,研究组BUT、SⅠT、NRA、AF、AMP均更高,而FL、PRA、立体视水平更低(P<0.05).结论 在白内障术后干眼症患者的治疗中,应用人工泪液联合普拉洛芬可提升治疗效果,能够改善患者干眼症状以及视功能,提高患者泪液分泌水平,且安全性较高.

Objective To analyze the effect of artificial tears combined with pranoprofen on the recovery of visual function quality in patients with dry eye after cataract surgery.Methods The study subjects were 260 patients with dry eye disease after cataract surgery admitted to Qinghai Oilfield Hospital from January 2020 to December 2024.By using the random number table method,patients were divided into two groups(a control group and a study group),each group had 130 patients.The control group was treated with artificial tears,while the study group was additionally administered pranoprofen eye drops on the basis of the treatment received by the control group,and comparisons were made between the two groups in terms of clinical efficacy,dry eye symptom scores,and improvements in tear secretion indexes[tear break-up time(BUT),corneal fluorescein staining(FL)and Schirmer Ⅰ test(SⅠT),as well as visual function parameters[negative relative accommodation(NRA),positive relative accommodation(PRA),accommodative facility(AF),amplitude of accommodation(AMP)and stereopsis].Results Compared with the control group,in which the total effective rate was 75.38%,the study group demonstrated a significantly higher total effective rate of 96.92%(P<0.05).The dry eye symptom score in the study group was significantly lower than that in the control group after 2 and 4 weeks of treatment(P<0.05).Meanwhile,regarding the visual function indicators after treatment,the study group showed significantly higher levels of BUT,SⅠT,NRA,AF and AMP,as well as significantly lower levels of FL,PRA,and stereopsis compared with the control group(P<0.05).Conclusion In the treatment of patients with dry eye after cataract surgery,the application of artificial tears combined with pranoprofen can improve the therapeutic effect,alleviate dry eye symptoms,improve visual function,increase tear secretion,and is associated with favorable safety.

刘战强;祁永兰

青海油田医院眼科,甘肃 敦煌 736202青海油田医院眼科,甘肃 敦煌 736202

医药卫生

白内障术后干眼症人工泪液普拉洛芬

Dry eye after cataract surgeryArtificial tearsPranoprofen

《医学信息》 2026 (8)

130-134,5

10.3969/j.issn.1006-1959.2026.08.024

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