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基于"态靶理论"探析慢性心力衰竭的临证辨治思路OA

Analyzing the Clinical Thinking of Treating Chronic Heart Failure Based on"State-Target"Theory

中文摘要英文摘要

慢性心力衰竭作为多种心脏疾病的终末阶段,以"阳虚瘀水互结"为核心病机贯穿病程始终.因其症状的难控性和迁延性,临床治疗慢性心衰以多脏器共治与重点治心为主.运用"态靶辨治"理念治疗慢性心力衰竭,通过构建宏观病情评估与微观靶向治疗有机结合的独特诊疗模式,以病理产物辨瘀态、水态、痰态,以历代医家古籍古方辨证,根据症状变化及理化指标辨靶,探讨"靶方""靶药"对于慢性心衰各阶段尤其是瘀态、水态的疗效,为治疗慢性心衰提供新的思路与方向.

Chronic heart failure,as the terminal stage of various cardiac diseases,is characterized by the core pathogene-sis of"mutual entanglement of Yang deficiency and stasis-fluid"throughout its course.Due to the intractability and protracted nature of its symptoms,clinical management of chronic heart failure primarily involves multi-organ co-treat-ment with a focus on cardiac therapy.The"State-Target Differentiation and Treatment"approach to chronic heart fail-ure establishes a unique diagnostic and therapeutic model integrating macro-level disease assessment with micro-level targeted therapy.It identifies stasis states,fluid states,and phlegm states through pathological products;differentiates syndromes using classical texts and formulas from historical physicians;and pinpoints targets based on symptom evolu-tion and biochemical indicators.This approach explores the efficacy of"target formulas"and"targeted drugs"across chronic heart failure stages-particularly in stasis and fluid states-offering novel therapeutic perspectives and directions.targeted medicationsin various stages of chronic heart failure,particularly for stasis and fluid retention states,offering novel therapeutic approaches and directions.

柯诗嫣;王梓伊;王力栋;刘强

浙江中医药大学附属第三医院,浙江 杭州 310052浙江中医药大学附属第三医院,浙江 杭州 310052浙江中医药大学附属第三医院,浙江 杭州 310052浙江中医药大学附属第三医院,浙江 杭州 310052

医药卫生

慢性心力衰竭态靶理论靶方靶药

chronic heart failurestate-target theorytarget formulastarget drugs

《亚太传统医药》 2026 (5)

196-199,4

浙江省卫生高层次创新人才项目(浙卫办2022-32号)

10.11954/ytctyy.202605036

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