首页|期刊导航|亚太传统医药|从燥热怫郁理论探讨2型糖尿病合并勃起功能障碍

从燥热怫郁理论探讨2型糖尿病合并勃起功能障碍OA

Exploring Type 2 Diabetes Mellitus with Erectile Dysfunction from the Perspective of Dryness-Heat and Depression Theory

中文摘要英文摘要

勃起功能障碍(ED)是男性2型糖尿病(T2DM)患者在病程后期出现的一种具有普遍性、易发性、难治性的微血管并发症.并且ED的常规治疗药物——5型磷酸二酯酶抑制剂对该类患者难以取得满意疗效.刘完素在《三消论》中首次提出"燥热怫郁"理论,对于防治T2DM 合并ED有重大意义.现代医学研究表明,中医燥热怫郁病机进展与现代医学慢性炎症具有显著相关性.基于"燥热怫郁"理论,系统阐释该病病程中燥热怫郁病机的转化规律,结合现代药理学研究成果,构建"开郁通腑-养阴清热-益气活血-温阳通络"的辨治方案,为中西医协同干预ED提供理论依据与实践参考.

Erectile dysfunction(ED)is a common,prevalent,and refractory microvascular complication among male patients with type 2 diabetes mellitus(T2DM),particularly in the advanced stages of the disease.Conventional treat-ment with phosphodiesterase type 5 inhibitors often yields unsatisfactory outcomes in this population.Liu Wansu first proposed the theory of"dryness-heat stagnation"in his work Sanxiao Lun,which holds significant implications for the prevention and treatment of T2DM complicated with ED.Modern medical research has demonstrated a notable correla-tion between the pathogenesis of dryness-heat stagnation in traditional Chinese medicine and chronic inflammation in modern medicine.Based on the theory of"dryness-heat stagnation,"this study systematically elucidates the evolution-ary pattern of this pathogenesis throughout the disease course.Integrating modern pharmacological research,we have established a staged treatment protocol:"dispersing stagnation and unblocking the Fu-Organs-nourishing Yin and clear-ing heat-supplementing Qi and activating blood circulation-warming Yang and dredging collaterals."This approach provides a theoretical foundation and a practical pathway for integrated traditional Chinese and Western medicine inter-ventions.

陆冰冰;杨怡;杨华;彭恋;陈其华

湖南中医药大学 第一中医临床学院,湖南 长沙 410007湖南中医药大学 第一中医临床学院,湖南 长沙 410007湖南中医药大学 第一中医临床学院,湖南 长沙 410007湖南中医药大学 第一中医临床学院,湖南 长沙 410007湖南中医药大学第一附属医院 男科,湖南 长沙 410007

医药卫生

燥热怫郁理论2型糖尿病勃起功能障碍慢性炎症

Dryness-Heat Stagnation TheoryType 2 Diabetes MellitusErectile DysfunctionChronic Inflammation

《亚太传统医药》 2026 (4)

170-174,5

国家自然科学基金(U24A20790)陈其华全国名老中医药专家传承工作室建设项目(04-022)湖南省自然科学基金青年基金项目(2022JJ40335)代谢性疾病中医药调控四川省重点实验室开放基金项目(SZKF202208)湖南省研究生科研创新项目(CX20230810)湖南省男性疾病中医临床医学研究中心项目(2018SK4012)湖南中医药大学创新训练项目(X202410541172)

10.11954/ytctyy.202604031

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