超声弹性成像联合超声引导下细针穿刺活检对甲状腺结节良恶性的鉴别诊断价值OA

Objective To explore the application value of ultrasound elastography(UE)combined with ultrasound-guided fine needle aspiration biopsy(US-FNAB)in the differential diagnosis of benign and malignant thyroid nodules.Methods Clinical data of 80 patients with thyroid nodules admitted to the 907th Hospital of the Joint Logistics Support Force from October 2022 to October 2025 were retrospectively collected.A total of 92 thyroid nodules were detected in these patients,all of which were confirmed by surgical pathology.All patients underwent UE examination and US-FNAB examination preoperatively.Taking surgical pathological results as the diagnostic"gold standard",the diagnostic efficacy of UE combined with US-FNAB in differentiating benign and malignant thyroid nodules was analyzed.The differences in UE parameters and US-FNAB Bethesda grading distribution between benign and malignant thyroid nodules were compared.Results Pathological results showed that among the 92 thyroid nodules,41(44.57%)were malignant and 51(55.43%)were benign.UE combined with US-FNAB showed the highest diagnostic efficacy in differentiating benign and malignant thyroid nodules(P<0.05).In terms of UE parameters,elasticity score,strain ratio,proportion of blue area,and elasticity index were significantly higher in malignant nodules than those in benign nodules(P<0.05).Regarding US-FNAB Bethesda grading distribution,benign nodules were mainly distributed in Bethesda grade Ⅱ,while malignant nodules were mainly concentrated in Bethesda grades Ⅴ～Ⅵ.The distribution of Bethesda classifications between benign and malignant nodules showed significant difference(P<0.05).Conclusions The combined application of UE and US-FNAB can significantly improve the differential diagnosis efficiency of benign and malignant thyroid nodules,and the combined parameters of both methods provide important references for identifying benign and malignant thyroid nodules.