计算机辅助认知训练结合高压氧治疗对轻度认知功能障碍患者的疗效观察OA
Observation on the Efficacy of Computer-Assisted Cognitive Training Com-bined with Hyperbaric Oxygen Therapy for Patients with Mild Cognitive Im-pairment
目的 探讨计算机辅助认知训练结合高压氧治疗对轻度认知功能障碍患者的影响.方法 选取 2023 年 10 月到 2025年 6 月上海市同济大学附属普陀人民医院收治的 88 例轻度认知功能障碍患者,按随机数字表法分为对照组(44 例,高压氧治疗)和试验组(44 例,计算机辅助认知训练+高压氧治疗).比较训练前及训练后 1 个月、3 个月的认知功能、日常活动能力、炎性因子水平及临床疗效.结果 训练后 1 个月、3 个月,试验组的认知功能、日常活动能力高于对照组,炎性因子水平低于对照组(P<0.05);试验组的总有效率为 93.18%,高于对照组的 75.00%(P<0.05).结论 高压氧治疗联合计算机辅助认知训练能够显著改善MCI患者的认知功能和日常生活能力,降低炎性因子水平,提高总体疗效.
Objective To investigate the effects of computer-assisted cognitive training combined with hyperbaric oxygen therapy on patients with mild cognitive impairment(MCI).Methods A total of 88 patients with mild cognitive impairment admitted to Putuo People's Hospital Affiliated to Tongji University,Shanghai,from October 2023 to June 2025,were selected and randomly divided into a control group(44 cases,hyperbaric oxygen therapy)and an experimental group(44 cases,computer-assisted cognitive training combined with hyperbaric oxygen therapy).Cognitive function,daily living ability,inflammatory factor levels,and clinical efficacy were compared before training and at 1 month and 3 months after training.Results At 1 month and 3 months after training,the experimental group showed higher cognitive function and daily living ability and lower inflammatory factor levels than the control group(P<0.05).The total effective rate in the experimental group was 93.18%,higher than 75.00%in the control group(P<0.05).Conclusions Hyperbaric oxygen therapy combined with computer-assisted cognitive training can significantly improve cognitive function and daily living ability in patients with MCI,reduce inflammatory factor levels,and enhance overall clinical efficacy.
顾静岚;赵芳
同济大学附属普陀人民医院 老年内科,上海 200072同济大学附属普陀人民医院 老年内科,上海 200072
医药卫生
轻度认知功能障碍计算机辅助认知训练高压氧认知功能日常活动能力
Mild cognitive impairmentComputer-assisted cognitive trainingHyperbaric oxygenCognitive functionDaily activity ability
《临床医学工程》 2026 (4)
449-453,5
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