昌都地区变应性鼻炎儿童尘螨过敏筛查及舌下脱敏短期疗效研究OA

Objective To understand the dust mite allergy situation of children with allergic rhinitis in the Qamdo area and the effect of sublingual desensitization therapy.Methods A total of 300 children with al-lergic rhinitis who visited the Pediatrics Department of People's Hospital of Qamdo City from January 2024 to March 2025 were selected as the research subjects and underwent dust mite skin prick tests.Based on the test results,78 cases of children with allergic rhinitis with strong positive or extremely strong positive dust mite reactions were randomly divided into the control group and the observation group,with 39 cases in each group.The control group received only conventional treatment,while the observation group was given sublin-gual desensitization therapy in addition to the conventional treatment.The pediatric outpatient clinic conducted regular follow-ups for 6 months.The therapeutic effect was evaluated based on the child's symptom control level,medication usage,and the incidence of adverse reactions.Results Among 300 children with allergic rhi-nitis,the detection rate of dust mite allergy was 31.3%(94/300),among which 16 cases(17.0%)were posi-tive for dust mites,and 78 cases(83.0%)were strongly positive or extremely strongly positive.After 6 months of follow-up,the results showed that there were statistically significant differences in symptom scores and drug use scores between the observation group and the control group(P<0.05),while the incidence of ad-verse reactions between two groups showed no statistically significant difference(P>0.05).Conclusion In the Qamdo area,the incidence of dust mite allergy in children with allergic rhinitis is relatively high,and the proportion of strongly positive-extremely positive is relatively high.In the short term,conventional treatment combined with sublingual desensitization therapy can more effectively control symptoms and reduce drug use,without increasing the incidence of adverse reactions.