钛基牙种植体表面改性促进软组织封闭的研究进展OA
Surface Modification of Titanium-based Dental Implants for Soft Tissue Sealing:A Review
钛及钛合金因其优异的力学性能、耐腐蚀性和生物相容性,被广泛用作牙种植体材料.然而,钛基牙种植体在临床使用中软组织封闭不佳,易使细菌侵入诱发种植体周炎,导致种植体植入手术失败.因此,为提升钛基牙种植体的软组织封闭性能,降低种植体植入手术的失败率,国内外学者开展了持续、深入的研究.本文综述了近年来钛基牙种植体软组织封闭表面改性研究系列进展,着重介绍了钛表面化学组分调控和微纳结构构建方法,指出了当前研究面临的挑战以及未来发展趋势,以期为该领域的进一步研究提供参考.
Titanium and its alloys are widely used as dental implant materials due to their excellent mechanical property,corrosion resistance and biocompatibility.However,in clinical applications,titanium-based dental implants often suffer from poor soft tissue sealing,allowing bacteria to invade and induce peri-implantitis,and leading to final implant failure.To address these issues and effectively reduce the failure rate of implant surgery,researchers worldwide have conducted extensive and in-depth studies.This article reviews recent advancements in surface modification strategies for improving soft tissue sealing on titanium-based dental implants,with a focus on methods for regulating surface chemical composition and constructing micro-nano structures.Additionally,it highlights the existing challenges and future trends in this field,aiming to provide valuable insights for further research on soft tissue sealing of titanium-based dental implants.
李璇;叶奎材;冯佳音;邱家军;钱文昊;邢敏
上海市徐汇区口腔医院 口腔生物材料与组织再生实验室,上海 200032||东华大学 生物与医学工程学院,上海 201620上海市徐汇区口腔医院 口腔生物材料与组织再生实验室,上海 200032上海市徐汇区口腔医院 口腔生物材料与组织再生实验室,上海 200032中国科学院 上海硅酸盐研究所,生物材料与组织工程研究中心,上海 200050上海市徐汇区口腔医院 口腔生物材料与组织再生实验室,上海 200032上海市徐汇区口腔医院 口腔生物材料与组织再生实验室,上海 200032
化学化工
钛种植体软组织封闭抗菌作用表面改性综述
titaniumimplantsoft tissue sealingantibacterial effectsurface modificationreview
《无机材料学报》 2026 (4)
432-444,13
国家自然科学基金(52272283)上海市徐汇区牙病防治所医学科研项目(SHXYFJX202501) National Natural Science Foundation of China(52272283)Medical Research Project of Shanghai Xuhui District Dental Center(SHXYFJX202501)
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