炒草果仁饮片的炮制工艺优化及质量标准研究OA
Optimization of Processing Technology and Establishment of Quality Standards for Stir-fried Amomum tsaoko Kernel
为优选炒草果仁的炮制工艺,建立炒草果仁饮片质量标准.本研究以浸出物、挥发油含量、儿茶素和表儿茶素含量作为评价指标,采用正交试验设计考察炒制温度、炒药时间和翻炒频率对炒草果仁炮制工艺的影响,确定炒草果仁的最佳炮制工艺参数.按照最佳工艺将10批草果仁饮片进行炮制,并建立炒草果仁质量标准草案.结果表明:炒草果仁最佳炮制工艺为80 ℃炒制15min,翻炒频率为20r/min,并通过中试生产验证,证明该炮制工艺稳定可行.依据14批炒草果仁饮片建立的质量标准,水分含量上限为10%,总灰分上限为6%,挥发油含量不少于0.8%,儿茶素与表儿茶素总含量不少于0.12%.本研究建立的炒草果仁炮制工艺稳定、可靠、易操作;所制定的炒草果仁饮片质量标准可为新版《吉林省中药饮片炮制规范》的修订提供参考.
This study to optimize the processing technology for stir-fried Amomum tsaoko kernel and to establish quality standards for the sliced medicinal pieces.This study taking the extract,volatile oil content,catechin and epicatechin as the evaluation indexes,the orthogonal test design was used to investigate the effects of stir-frying temperature,stir-frying time and stir-frying frequency on the processing technol-ogy of stir-fried Amomum tsaoko kernels,and the optimum processing parameters of stir-fried Amomum tsaoko kernels were determined.According to the best process,10 batches of Amomum tsaoko kernels decoction pieces were processed,and a draft quality standard for stir-fried Amomum tsaoko kernel was established.The optimal processing technique for stir-fried Amomum tsaoko kernel is to fry them at 80 ℃for 15 minutes with a turning frequency of 20 revolutions per minute.This method has been validated through pilot-scale production,proving the stability and feasibility of the processing technique.Quality standards have been established for 14 batches of stir-fried Amomum tsaoko kernel,stipulating that the moisture content should not exceed 10%,the total ash content should not exceed 6%,the volatile oil content should be no less than 0.8%,and the combined content of catechin and epicatechin should be no less than 0.12%.The orthogonal experiment method was employed to optimize the processing technique for fried Amomum tsaoko seeds,resulting in a stable,reliable,and easily operable pro-cedure.Additionally,the established quality standards for fried Amomum tsaoko seed slices provide a reference for the revision of the new edition of the Jilin Province Traditional Chinese Medicine Decoction Pieces Processing Specifications.
马晓静;崔业波;宋瑩;王丹彧;马彧
四平市食品药品检验所,吉林 四平 136000四平市食品药品检验所,吉林 四平 136000四平市食品药品检验所,吉林 四平 136000四平市食品药品检验所,吉林 四平 136000四平市食品药品检验所,吉林 四平 136000
医药卫生
炒草果仁儿茶素表儿茶素薄层色谱法高效液相色谱法
stir-fried Amomum tsaoko kernelcatechinepicatechinTLCHPLC
《特产研究》 2026 (2)
104-111,8
吉林省药品监督管理局中药材及中药饮片炮制规范项目(JLPZGF-2021-008)
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