首页|期刊导航|实用中医内科杂志|张晓春教授从标本同治理论辨治恶性肿瘤后神经毒性经验浅析

张晓春教授从标本同治理论辨治恶性肿瘤后神经毒性经验浅析OA

Professor Zhang Xiaochun Analyzes the experience of Treating Neurotoxicity after Malignant Tumor from the Perspective of Specimen and Treatment

中文摘要英文摘要

恶性肿瘤治疗手段如放疗、化疗等可致中枢和周围神经系统损伤,患者常出现麻木、疼痛等症状,神经毒性是肿瘤治疗中的常见并发症,在中医中属于"痹症"的范畴.现代医学对症治疗的疗效常不甚理想.张教授提出其核心病机在于"气血两虚,痰瘀互结".治疗应分清急缓虚实,标本同治,以调补气血、固护脾胃治其本,以化痰逐瘀、通络止痛治其标,尤重"健脾"在调和气血、运化痰瘀中的核心作用.内服中药为主,以黄芪桂枝五物汤为基础方随症加减,如用川桂枝、黄芪、川芎等以温经通脉、畅达气机、活血化瘀.张教授还注重外治法,采用中药熏洗疗法,通过温热作用直接作用于病变肢体,促进血液循环、疏通经络.临床验案显示,此法可有效缓解患者四肢麻木、疼痛等症状,恢复肢体温度感,改善生活质量,反映了中医的"整体观念、标本同治"的理念,为恶性肿瘤治疗后神经毒性的治疗提供了新的思路和方法.

Treatment modalities for malignant tumors,such as radiotherapy and chemotherapy,can cause damage to the cen-tral and peripheral nervous systems,often leading to symptoms like numbness and pain.Neurotoxicity is a common complication in tumor therapy and falls under the category of "bi syndrome"in Traditional Chinese Medicine(TCM).Modern medicine often demonstrates limited efficacy in symptomatic treatment.Professor Zhang posits that the core pathogenesis lies in "deficiency of both qi and blood,with phlegm and stasis intermingling."Treatment should differentiate between acute and chronic conditions,addressing both symptoms and root causes.The fundamental approach involves regulating and replenishing qi and blood,as well as fortifying the spleen and stomach to address the root cause,while the symptomatic approach focuses on resolving phlegm,dis-pelling stasis,and unblocking collaterals to alleviate pain.Particular emphasis is placed on the pivotal role of "strengthening the spleen"in harmonizing qi and blood and transforming phlegm and stasis.Oral administration of Chinese herbal medicine is the primary method,with Huangqi Guizhi Wuwu Decoction as the base formula,modified according to symptoms.For instance,herbs like Chuan Guizhi,Huangqi,and Chuanxiong are used to warm the meridians,promote qi circulation,and activate blood to resolve stasis.Professor Zhang also emphasizes external therapies,employing herbal fumigation and washing to directly act on the affected limbs through thermal effects,thereby improving blood circulation and unblocking collaterals.Case studies have shown significant efficacy,with patients experiencing marked relief from limb numbness,absence of pain,restoration of tempera-ture sensation,and substantial improvement in quality of life.This reflects the TCM philosophy of "holistic treatment and ad-dressing both symptoms and root causes,"providing new insights and methods for managing neurotoxicity following malignant tumor treatment.

周雲霞;吴双;刘真理;葛志颖;何莉;李念;张晓春

南京中医药大学扬州附属医院,江苏 扬州 225100扬州大学医学院,江苏 扬州 225100南京中医药大学扬州附属医院,江苏 扬州 225100南京中医药大学扬州附属医院,江苏 扬州 225100南京中医药大学扬州附属医院,江苏 扬州 225100扬州大学医学院,江苏 扬州 225100南京中医药大学扬州附属医院,江苏 扬州 225100||扬州大学医学院,江苏 扬州 225100||江苏省扬州市中医院,江苏 扬州 225100

医药卫生

恶性肿瘤神经毒性健脾标本同治张晓春名中医

Malignant tumorNeurotoxicitySpecimen and treatmentTonifying spleenZhang XiaochunFamous TCM doctor

《实用中医内科杂志》 2026 (4)

71-74,4

第四批省名老中医药专家传承工作室(张晓春)(GZS20220628001)国家中医优势专科建设单位项目(GJZYYSZKJS-ZLK)

10.13729/j.issn.1671-7813.Z25053003

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