骨盆包虫病患者32例的治疗及预后因素分析OA
Analysis of treatment and prognostic factors in 32 cases of pelvic hydatid disease
目的 分析骨盆包虫病的临床特点、治疗效果及预后影响因素,总结其高复发背景下的临床诊治经验.方法 回顾性分析2000年1月至2023年12月收治的32例骨盆包虫病患者资料.采用Spearman相关分析手术与复发次数的关系,并通过多因素Logistic回归分析筛选治愈的独立预测因素.结果 患者平均年龄(32.56±13.45)岁,主要临床表现为髋部、腰骶部或下肢疼痛,其中2例(6.3%)出现截瘫及大小便失禁等严重并发症.30例(93.75%)患者接受手术治疗,平均手术(3.09±1.85)次.全组复发率高达84.4%(27/32),而治愈率仅为25.0%(8/32).Spearman相关分析显示,手术次数与复发次数呈强正相关(r=0.828,P<0.001).多因素Logistic回归分析证实,年龄是治愈的独立保护因素(OR=1.129,95%CI:1.026~1.242,P=0.013).结论 骨盆包虫病临床表现以疼痛为主,但可致严重神经损害,其特点是复发率高、治愈率低.高龄可能是治愈的正向因素,而反复手术与复发紧密关联,这凸显了初次治疗彻底性的至关重要性.
Objective To analyze the clinical characteristics,treatment outcomes,and prognostic factors of pelvic hydatid disease,and to summarize the experience of diagnosis and treatment in the context of high recurrence rate.Methods A retrospective analysis of 32 patients with pelvic hydatid disease treated between January 2000 and December 2023 was conducted.Spearman correlation analysis was used to assess the relationship between surgery and recurrence frequency,and multivariate Logistic regression analysis was per-formed to identify independent predictors of cure.Results The mean age of the patients was 32.56±13.45 years.The main clinical manifestations were pain in the hip,lumbosacral region,or lower limbs,and two cases(6.3%)presented severe complications such as paraplegia and urinary/fecal incontinence.Thirty patients(93.75%)underwent surgical treatment,with a mean number of 3.09±1.85 surgeries per patient.The overall recurrence rate was 84.4%(27/32),while the cure rate was only 25.0%(8/32).Spearman correlation analysis revealed a strong positive correlation between the number of surgeries and recurrence frequency(r=0.828,P<0.001).Multi-variate Logistic regression analysis confirmed that age was an independent protective factor for cure(OR=1.129,95%CI:1.026-1.242,P=0.013).Conclusion Pelvic hydatid disease primarily presents with pain but may lead to severe neurological damage.It is charac-terized by a high recurrence rate and a low cure rate.Advanced age may be a positive factor for cure,while repeated surgeries are strongly associated with recurrence,underscoring the critical importance of thorough initial treatment.
周子钰;董士铭;谢增如
新疆医科大学第一附属医院创伤骨科,乌鲁木齐 830011新疆医科大学第一附属医院脊柱外科新疆医科大学第一附属医院创伤骨科,乌鲁木齐 830011
医药卫生
骨盆包虫病手术治疗复发预后危险因素
pelvic hydatid diseasesurgeryrecurrenceprognosisrisk factors
《山西医科大学学报》 2026 (3)
333-337,5
国家自然科学基金项目(82260409)
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