乌司他丁辅助治疗老年重症肺炎的最新应用进展OA
The Latest Application Progress of Ulinastatin in The Adjuvant Treatment of Severe Pneumonia in The Elderly
重症肺炎是老年群体常见的一种患病率高、死亡率高的严重感染性疾病.由于老年人存在自身免疫功能减退、基础疾病多、器官功能储备差等特点,导致治疗难度大、预后差.乌司他丁是从人尿中提取的多肽类药物,具有广泛的生物学活性,在抗炎、抗氧化、器官保护等方面功能显著.在老年重症肺炎患者治疗中辅助使用乌司他丁,不仅能快速改善患者临床症状,还能缩短其治疗时间,提高治疗有效性和安全性.本文对乌司他丁辅助治疗老年重症肺炎的最新应用进展进行综述.
Severe pneumonia is a common serious infectious disease with high morbidity and mortality in the elder-ly.Because the elderly have the characteristics of decreased autoimmune function,many basic diseases and poor or-gan function reserve,it is difficult to treat and the prognosis is poor.Ulinastatin is a polypeptide drug extracted from human urine,which has a wide range of biological activities and significant functions in anti-inflammatory,anti-oxidation and organ protection.The adjuvant use of ulinastatin in the treatment of elderly patients with se-vere pneumonia can not only improve the clinical symptoms of patients quickly,but also shorten the treatment time and improve the effectiveness and safety of treatment.This paper reviews the latest application progress of ulinas-tatin in the adjuvant treatment of severe pneumonia in the elderly.
李慧婷;李军
承德医学院,河北 承德 067000承德医学院附属医院全科医疗科,河北 承德 067000
医药卫生
乌司他丁老年重症肺炎药理机制应用进展
UlinastatinSevere pneumonia in the elderlyPharmacological mechanismApplication progress
《生命科学仪器》 2026 (2)
140-142,3
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