电针联合五禽戏对帕金森病患者运动功能和手功能的影响OA

Objective To observe the effect of electroacupuncture combined with Wu Qin Xi(Five-animal Exercises)on motor function and hand function in patients with Parkinson's disease,as well as its effect on serum gamma-glutamyl transpeptidase(GGT)and growth differentiation factor 15(GDF-15)levels.Method A total of 82 patients with Parkinson's disease were randomly divided into an exercise group and a combined group,with 41 cases in each group.The exercise group received Wu Qin Xi exercise intervention,while the combined group received electroacupuncture in addition to the Wu Qin Xi exercise intervention used in the exercise group.Changes in motor function[unified Parkinson's disease rating scale(UPDRS)parts Ⅰ,Ⅰ and Ⅲ scores],hand function[soda pop test(SPT)and Purdue pegboard test(PPT)results],oxidative stress indices[superoxide dismutase(SOD),malondialdehyde(MDA),and glutathione peroxidase(GSH-Px)],neurotrophic factor indices[brain-derived neurotrophic factor(BDNF),neurotrophin-3(NT-3),nerve growth factor(NGF),and neuron-specific enolase(NSE)],and serum GGT and GDF-15 levels were observed before and after treatment.Result After treatment,UPDRS parts Ⅰ,Ⅱ and Ⅲ scores,MDA,NSE,GGT,and GDF-15 levels decreased in both groups(P＜0.05),and these indicators in the combined group were lower than those in the exercise group(P＜0.05).SPT,PPT,SOD,GSH-Px,BDNF,NT-3,and NGF levels increased in both groups(P＜0.05),and these indicators in the combined group were higher than those in the exercise group(P＜0.05).Conclusion Electroacupuncture combined with Wu Qin Xi intervention can improve motor function and hand function in patients with Parkinson's disease,reduce oxidative stress injury,and decrease serum GGT and GDF-15 levels.