海洋生物来源抗肿瘤寡肽的研究进展OA

Cancer remains one of the leading causes of mortality worldwide,making the development of antineoplastic drugs a critical focus in medical research.In recent years,the unique and complex characteristics of marine organisms have attracted increasing attention,prompting extensive exploration of their bioactive compounds.Numerous studies have demonstrated that oligopeptides derived from marine organisms can exert anti-tumor effects through the induction of apoptosis.Small molecular peptides offer advantages such as rapid absorption and efficient cellular and tissue penetration,making them promising candidates for targeted anti-cancer therapies.However,the identification and underlying mechanisms of action of marine-derived oligopeptides are still under investigation.This article provides a comprehensive review of anti-tumor oligopeptides isolated from various marine species,categorized by their biological sources.