微流体纺丝改进氧化钛纳米晶须SERS性能的重复性OACHSSCD

The reproducibility of substrates for surface-enhanced Raman spectroscopy(SERS)is a key barrier to their applications.This study aims to improve the stability of SERS signals produced by TiO2 nanowhiskers and to increase their enhancement factor(EF).We used microfluidic spinning to generate spatially ordered arrays of TiO2 nanowhiskers and investigated how whisker mass concentration and heat-treatment temperature affect their morphology and SERS performance.The results show that microfluidic spinning successfully achieved the directional alignment of TiO2 nanowhiskers,with SEM images revealing a transition from disordered whiskers to uniform and ordered TiO2 whisker arrays,resulting in a significant enhancement in SERS performance.Using methylene blue(MB)as the probe molecule,the ordered substrate(S-TiO2)achieved a relative standard deviation(RSD)of 17.16％,and its EF increased from 7.5 × 105 to 1.4 × 106.Optimization indicates that a TiO2 nanowhisker concentration of 10 mg/mL and a heat-treatment temperature of 500 ℃ produce the highest structural order and the strongest SERS signals.These findings demonstrate that microfluidic spinning can effectively enhance the reproducibility of semiconductor-based SERS substrates by inducing ordered nanostructure alignment,providing a general and low-cost strategy for producing semiconductor-based SERS substrates.