代谢紊乱背景下心脑血管病治则由"活血化瘀"向"痰瘀同治"转化的探讨OA

The pathogenesis of cardiovascular and cerebrovascular diseases in traditional Chinese medicine(TCM)has been evolving constantly with the changes in lifestyles and disease patterns.The classical theory highlights blood stasis as their core pathogenesis and treats them by promoting blood circulation.With the changes in modern lifestyle and diet structure,metabolic disorders play an increasingly prominent role in the occurrence and development of these diseases.It is held in traditional Chinese medicine that the viscous and obstructive characteristics caused by the accumulation of metabolic products correspond to the pathological attribute of endogenous turbid phlegm.Accordingly,their core pathogenesis has shifted from simple blood stasis to intermingled phlegm and blood stasis,while their therapeutic strategies transmit as well from activating blood circulation alone to resolving both phlegm and blood stasis.Based on a review of the pathogenesis evolution of cardio-cerebrovascular diseases,combined with the background of metabolic disorders,this study re-examines their core pathogenesis of intermingled phlegm and blood stasis,in a bid to provide theoretical references for future research on their related treatment methods and principles.