基于胎儿血流动力学参数的超声多模态模型在子痫前期风险的预测研究OA

Objective Construct and analyze the application value of the ultrasound multimodal model based on fetal hemodynamic parameters in predicting the risk of severe preeclampsia.Method The cross-sectional data of 74 pregnant women with severe preeclampsia who had regular prenatal examinations and delivered in our hospital from January were selected as the observation group,and another 50 pregnant women with normal prenatal examinations during the same period were selected as the control group.The general data of the two groups and the fluid dynamics parameters of the fetus were analyzed.Multiple regression analysis was used to analyze the factors influencing the occurrence of preeclampsia in pregnant women;Build a prediction model based on influencing factors and analyze its prediction efficacy.Result The levels of BMI,SBP and DBP in the preeclampsia group were significantly higher than those in the control group,while the gestational age at delivery was lower(P<0.05).The PI(1.37±0.13),RI(0.81±0.19)and S/D(3.67±0.43)of the umbilical artery in the preeclampsia group were all higher than those in the control group.However,the PI(1.08±0.16),RI(0.54±0.19),and S/D(2.42±0.31)of the fetal middle cerebral artery were lower than those of the control group(P<0.05);The results of multiple regression analysis showed that a high level of umbilical artery PI,RI,and S/D ratio in the fetus was a risk factor affecting the occurrence of preeclampsia in pregnant women.The high levels of PI,RI and S/D ratio of the fetal middle cerebral artery are its protective factors;Based on the influencing factors,a prediction model equation was constructed,Y=3.063×PI of the umbilical artery+1.051×S/D ratio of the umbilical artery+2.061×RI of the umbilical artery+2.610×PI of the fetal middle cerebral artery+3.762×RI of the fetal middle cerebral artery+2.783×S/D ratio of the fetal middle cerebral artery-2.618;The ROC curve indicated that the predictive model had a good predictive efficacy for preeclampsia in pregnant women(AUC=0.856),P<0.05.Conclusion Fetal hemodynamic parameters can be used as important indicators for the early identification of high risk.The high levels of umbilical artery PI,RI,and S/D ratios in the fetus are risk factors affecting the occurrence of preeclampsia in pregnant women.The high levels of PI,RI and S/D ratio of the fetal middle cerebral artery are its protective factors.Based on the influencing factors,The constructed prediction model has high prediction efficiency,which can improve early warning ability and provide basis for clinical intervention.