首页|期刊导航|西部中医药|腹式呼吸训练干预对糖尿病终末期肾脏病透析患者的康复效能研究

腹式呼吸训练干预对糖尿病终末期肾脏病透析患者的康复效能研究OA

Study on the Rehabilitation Efficacy of Abdominal Breathing Training Intervention in Patients with Diabetic End-Stage Renal Disease Undergoing Dialysis

中文摘要英文摘要

目的:探讨腹式呼吸训练对糖尿病终末期肾脏病血液透析患者康复效能的改善作用.方法:选取糖尿病终末期肾脏病血液透析患者50例作为研究对象,采用随机化方法分为对照组和试验组,每组25例.对照组给予常规血液透析治疗,试验组在对照组基础上联合传统气功腹式呼吸训练,两组均干预8周.观察并比较两组患者干预前后的肾功能指标[血肌酐(serum creatinine,SCr)、血清尿素氮(blood urea nitrogen,BUN)]、炎症指标[C反应蛋白(C-reactive protein,CRP)、白细胞总数(white blood cell count,WBC)、中性粒细胞百分比(neutrophil percentage,NE%)、淋巴细胞百分比(lymphocyte percentage,LYM%)、单核细胞百分比(monocyte percentage,MONO%)]、心脑血管疾病相关指标[同型半胱氨酸(homocysteine,Hcy)]及血糖指标[空腹血糖(glucose,Glu)].结果:肾功能指标方面,干预8周后,两组BUN均呈下降趋势,差值分析显示试验组下降幅度显著大于对照组(P<0.05);两组SCr干预后略有上升,组间比较差异无统计学意义(P<0.05).炎症指标方面,干预4、8周后,两组CRP均呈下降趋势,试验组下降幅度显著大于对照组(P<0.05);两组WBC、NE%、LYM%、MONO%均无明显变化,组间比较差异无统计学意义(P<0.05).心脑血管疾病相关指标方面,两组基线期Hcy水平比较差异有统计学意义(P<0.05),干预期间对照组Hcy呈上升趋势、试验组呈下降趋势,差值分析显示干预4、8周后试验组变化幅度显著大于对照组(P<0.05).血糖指标方面,试验组Glu呈下降趋势,且下降幅度显著大于对照组(P<0.05).两组均未出现不良反应.结论:在中医"金水相生"的理论指导下,传统气功腹式呼吸法可有效降低血糖、改善其肾功能、减轻炎症反应、有助于降低心血管风险指标.

Objective:To investigate the improving effect of abdominal breathing training on the rehabilita-tion efficacy of patients with diabetic end-stage renal disease undergoing hemodialysis.Methods:Fifty patients with diabetic end-stage renal disease undergoing hemodialysis were selected as the study subjects and randomly divided into a control group and an experimental group,with 25 cases in each group.The control group received conventional hemodialysis treatment,while the experimental group received traditional Qigong abdominal breathing training in addition to the treatment given to the control group.Both groups were intervened for eight weeks.To observe and compare renal function indicators[serum creatinine(SCr),blood urea nitrogen(BUN)],inflammatory indicators[C-reactive protein(CRP),white blood cell count(WBC),neutrophil percentage(NE%),lymphocyte percentage(LYM%),monocyte percentage(MONO%)],cardiovascular and cerebrovascular disease-related indicators[homocysteine(Hcy)],and blood glucose indicators[glucose(Glu)]between the two groups before and after the intervention.Results:In terms of renal function indicators,after eight weeks of intervention,BUN levels showed a downward trend in both groups,and the difference analysis indicated that the decrease in the experimental group was significantly greater than that in the control group(P<0.05).SCr levels increased slightly in both groups after the intervention,with no statistically significant difference between the groups(P>0.05).Regarding inflammatory indicators,after four and eight weeks of intervention,CRP levels showed a downward trend in both groups,with the experimental group demonstrating a significantly greater decrease than the control group(P<0.05).No significant changes were observed in WBC,NE%,LYM%,or MONO%in either group,and the differences between the groups were not statistically significant(P>0.05).For cardiovascular and cerebro-vascular disease-related indicators,there was a statistically significant difference in baseline Hcy levels between the two groups(P<0.05).During the intervention period,Hcy levels showed an upward trend in the control group and a downward trend in the experimental group.Difference analysis revealed that the magnitude of change in the experimental group was significantly greater than that in the control group after four and eight weeks of intervention(P<0.05).In terms of blood glucose indicators,Glu levels showed a downward trend in the experimental group,with a significantly greater decrease compared to the control group(P<0.05).No adverse reactions occurred in either group.Conclusion:Guided by the traditional Chinese medicine theory of"mutual generation between metal and water,"the traditional Qigong abdominal breathing method can effectively lower blood glucose,improve renal function,reduce inflammatory responses,and help decrease cardiovascular risk indicators.

赵希瑞;吕天宜;吕嘉轩;王若水;魏玉龙

北京中医药大学针灸推拿学院,北京 102488北京中医药大学针灸推拿学院,北京 102488北京中医药大学针灸推拿学院,北京 102488北京中医药大学针灸推拿学院,北京 102488北京中医药大学针灸推拿学院,北京 102488

医药卫生

糖尿病终末期肾脏病血液透析腹式呼吸金水相生肾功能炎症指标同型半胱氨酸血糖

diabetic end-stage renal diseasehemodialysisabdominal breathingmutual generation between metal and waterrenal functioninflammatory factorsHcyblood glucose

《西部中医药》 2026 (4)

161-166,6

国家自然科学基金(82074514).

10.12174/j.issn.2096-9600.2026.04.35

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