化癥消积汤联合TACE治疗原发性肝癌湿热毒蕴证疗效分析OA

Objective:To analyze curative effects of masses-resolving and accumulation-dispelling decoction and TACE in treating primary liver cancer(PLC)with accumulated dampness,heat,toxin pattern.Methods:A total of 72 PLC patients were collected,and divided into the control group and the observation group according to random number table method with 36 cases in each.TACE was administered to the two groups for one therapeutic course;the control group accepted conventional measures of protecting liver and stomach after the operation,while the observation group adopted the same therapeutic measures as the control group,and took masses-resolving and accumulation-dispelling decoction orally.Both groups were treated for 12 weeks continuously.To compare clinical effects,liver function before and after the treatment,the scores of accumulated dampness,heat,toxin pattern,the scales of quality of life between the two groups.Results:After 12 weeks of the treatment in a row,total effective rate of the observation group was[72.22%(26/36)],higher than[44.44%(16/36)]of the control group(P<0.05);the reduction in AST,ALT and TBIL was seen in the two groups,and the decrease of the observation group was more evident than that of the control group(P<0.05);the scores of accumulated dampness,heat,toxin pattern were lowered while Karnofsky score were lifted in the observation group(P<0.05),and the improvement of the observation group was more significant than that of the control group(P<0.05).Conclusion:Masses-resolving and accumulation-dispelling decoction combined with TACE demonstrated noticeable clinical effects in treating PLC with accumulated dampness,heat,toxin pattern,it could improve liver function,relieve clinical symptoms and enhance quality of life.