急性冠脉综合征患者中医证型与GRACE评分及冠脉病变支数的相关性分析OA

Objective:To analyze the distribution of TCM syndromes in patients with ACS and the Influence of uncontrollable factors,such as gender,on disease occurrence and prognosis,with further exploration of the relationship between different TCM syndromes in ACS patients and the Global Registry of Acute Coronary Events(GRACE)score as well as the number of diseased coronary arteries.Methods:A retrospective analysis was conducted on 301 patients with ACS who underwent coronary angiography(CAG)in the Cardiology Department of the Affiliated Hospital of Liaoning University of Traditional Chinese Medicine from July 2017 to March 2021.Clinical data,including baseline information,electrocardiogram changes,biochemical tests,number of diseased coronary arteries,and TCM syndrome types,were collected at admission.The GRACE risk score was calculated for each patient,and risk stratification was recorded(high-risk group:>140 points;intermediate-risk group:109-140 points;low-risk group:<109 points).To analyze the correlation between GRACE score and the number of diseased coronary arteries in ACS patients with different TCM syndrome types,and to investigate the distribution of TCM syndrome types among ACS patients and the influence of uncontrollable factors,such as gender,on disease occurrence and prognosis.Results:Among the different TCM syndrome types,the most common was the phlegm-blood stasis syndrome,followed by the Qi stagnation and blood stasis syndrome.There was a statistically significant difference in the gender distribution among the different syndrome types(P<0.05).The number of diseased vessels varied across syndrome types,but aside from the Qi stagnation and blood stasis syndrome and the heart-kidney Yin deficiency syndrome,the differences were not statistically significant(P>0.05).The GRACE score risk stratification also differed among syndrome types;however,with the exception of the Qi-Yin deficiency syndrome,Qi stagnation and blood stasis syndrome,and phlegm-blood stasis syndrome,the differences were not statistically significant(P>0.05).Patients with a GRACE score≥164 had a higher risk of multivessel disease.Conclusion:There is a correlation between different TCM syndrome types and the GRACE score as well as the number of diseased coronary arteries.Among them,patients with the Qi stagnation and blood stasis syndrome mostly have single-vessel disease and a better prognosis.